CAS Number53-34-9
SynonymsF. I. 6150; fluprednisolone; EINECS 200-170-8; MFCD00200355; Isopredon; Prednisolone,6alpha-fluoro; 6alpha-Fluoroprednisolone; Etadrol; Vladicort; Alphadrol
Molecular FormulaC21H27FO5
Molecular Weight378.44
Purity98.00%
Density1.35 g/cm3
Boiling Point572.3ºC at 760 mmHg
Melting Point208 - 213ºC
EINECS200-170-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 53-34-9 |
| Catalog No. | 2A-9016645 |
| Chinese Name | 6-α-氟泼尼龙 |
| Synonyms | F. I. 6150; fluprednisolone; EINECS 200-170-8; MFCD00200355; Isopredon; Prednisolone,6alpha-fluoro; 6alpha-Fluoroprednisolone; Etadrol; Vladicort; Alphadrol |
| Molecular Formula | C21H27FO5 |
| Molecular Weight | 378.44 |
| Purity | 98.00 |
| Density | 1.35 g/cm3 |
| Boiling Point | 572.3ºC at 760 mmHg |
| Melting Point | 208 - 213ºC |
| Storage Condition | Room Temperature |
| Application | 6α-Fluprednisolone (fluprednisolone) is the internal standard for methylprednisolone, prednisolone, and prednisone. 6α-Fluprednisolone is an anti-inflammatory agent. 6α-Fluprednisolone can be used in |
| EINECS | 200-170-8 |
| MDL Number | C21H27FO5 |
| SMILES | CC12C=CC(=O)C=C1C(F)CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO |
| InChI | InChI=1S/C21H27FO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7,12-13,15-16,18,23,25,27H,4,6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1 |
| InChI Key | MYYIMZRZXIQBGI-HVIRSNARSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/16645_1_53_34_9.pdf |
| Bioactivity | 6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97. [2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82. [3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54. Chemical & Physical Properties Density 1.35 g/cm3 Boiling Point 572.3ºC at 760 mmHg Melting Point 208 - 213ºC Molecular Formula C21H27FO5 Molecular Weight 378.43400 Flash Point 299.9ºC Exact Mass 378.18400 PSA 94.83000 LogP 1.50560 Index of Refraction 1.597 InChIKey MYYIMZRZXIQBGI-HVIRSNARSA-N SMILES CC12C=CC(=O)C=C1C(F)CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO |
| Use of | 6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3]. Properties Name (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one Synonym More Synonyms Fluprednisolone Biological Activity Description 6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97. [2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82. [3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54. Chemical & Physical Properties Molecular Formula C21H27FO5 Exact Mass 378.18400 PSA 94.83000 LogP 1.50560 Index of Refraction 1.597 InChIKey MYYIMZRZXIQBGI-HVIRSNARSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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