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7-Hydroxy cholesterol structure, CAS 566-27-8

7-Hydroxy cholesterol

CAS Number566-27-8

Synonyms5-Cholestene-3β,7β-diol; 7β-hydroxycholesterol; 7BETA-HYDROXYCHOLESTEROL; 7β-Hydroxy Cholesterol; (3β,7β,8ξ)-Cholest-5-ene-3,7-diol

Molecular FormulaC27H46O2

Molecular Weight402.65

Purity≥95%

Density1.0±0.1 g/cm3

Boiling Point515.3±38.0 °C at 760 mmHg

Melting Point165-167ºC

Flash Point

Appearancepowder

EINECS

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Cat. No.: 2A-9022952 Purity: ≥95%
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Quality Control of [ 566-27-8 ] Purity: ≥95% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number566-27-8
Catalog No.2A-9022952
Chinese Name7β-羟基胆固醇
Synonyms5-Cholestene-3β,7β-diol; 7β-hydroxycholesterol; 7BETA-HYDROXYCHOLESTEROL; 7β-Hydroxy Cholesterol; (3β,7β,8ξ)-Cholest-5-ene-3,7-diol
Molecular FormulaC27H46O2
Molecular Weight402.65
Purity≥95
Density1.0±0.1 g/cm3
Boiling Point515.3±38.0 °C at 760 mmHg
Melting Point165-167ºC
Appearancepowder
Storage Condition-20°C, sealed, dry
Application7β-Hydroxycholesterol is an oxysterol derived from the oxidation of cholesterol. 7β-hydroxycholesterol is a powerful inducer of oxidative stress that can induce organelle (mitochondria, lysosomes, and
PubChem ID24895774
MDL NumberMFCD00058406
SMILES[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C
InChI1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3
InChI KeyOYXZMSRRJOYLLO-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC12352211
Hazard SymbolsTransport
MSDSmsds/22952_1_566_27_8.pdf
Bioactivity7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol is a powerful inducer of oxidative stress, inducing dysfunction of organelles (mitochondria, lysosomes and peroxisomes) that can cause cell death[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease References [1]. Anne Vejux, et al. 7-Ketocholesterol and 7β-hydroxycholesterol: In vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity. Biochem Pharmacol. 2020 Mar;173:113648. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 515.3±38.0 °C at 760 mmHg Melting Point 165-167ºC Molecular Formula C27H46O2 Molecular Weight 402.653 Flash Point 214.7±21.4 °C Exact Mass 402.349792 PSA 40.46000 LogP 7.94 Vapour Pressure 0.0±3.0 mmHg at 25°C Index of Refraction 1.536 InChIKey OYXZMSRRJOYLLO-KGZHIOMZSA-N SMILES CC(C)CCCC(C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C
Use of7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol is a powerful inducer of oxidative stress, inducing dysfunction of organelles (mitochondria, lysosomes and peroxisomes) that can cause cell death[1]. Properties Articles34 Name 7β-hydroxycholesterol Synonym More Synonyms 7Beta-Hydroxycholesterol Biological Activity Description 7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol is a powerful inducer of oxidative stress, inducing dysfunction of organelles (mitochondria, lysosomes and peroxisomes) that can cause cell death[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease References [1]. Anne Vejux, et al. 7-Ketocholesterol and 7β-hydroxycholesterol: In vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity. Biochem Pharmacol. 2020 Mar;173:113648. Chemical & Physical Properties Molecular Formula C27H46O2 Exact Mass 402.349792 PSA 40.46000 Index of Refraction 1.536 InChIKey OYXZMSRRJOYLLO-KGZHIOMZSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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