CAS Number574-84-5
SynonymsEINECS 209-376-2; 6-methoxy-7,8-dihydroxycoumarin; 7,8-Dihydroxy-6-methoxy-2H-chromen-2-one; 2H-1-Benzopyran-2-one,7,8-dihydroxy-6-methoxy; 7,8-Dihydroxy-6-methoxycoumarin; 7,8-dihydroxy-6-methoxy-benzopyran-2-one; 7,8-Dihydroxy-6-methoxy-2H-1-benzopyran-2-one; Fraxetin; MFCD00006873
Molecular FormulaC10H8O5
Molecular Weight208.17
Purity98%
Density1.5±0.1 g/cm3
Boiling Point472.0±45.0 °C at 760 mmHg
Melting Point230-231 °C (lit.)
Appearancepowder
EINECS209-376-2
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 574-84-5 |
| Catalog No. | 2A-9022994 |
| Chinese Name | 秦皮素 |
| Synonyms | EINECS 209-376-2; 6-methoxy-7,8-dihydroxycoumarin; 7,8-Dihydroxy-6-methoxy-2H-chromen-2-one; 2H-1-Benzopyran-2-one,7,8-dihydroxy-6-methoxy; 7,8-Dihydroxy-6-methoxycoumarin; 7,8-dihydroxy-6-methoxy-benzopyran-2-one; 7,8-Dihydroxy-6-methoxy-2H-1-benzopyran-2-one; Fraxetin; MFCD00006873 |
| Molecular Formula | C10H8O5 |
| Molecular Weight | 208.17 |
| Purity | 98 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 472.0±45.0 °C at 760 mmHg |
| Melting Point | 230-231 °C (lit.) |
| Appearance | powder |
| Storage Condition | Room temperature, sealed, protected from light, ve |
| Application | Fraxetin is isolated from Cortex Fraxini. Fraxetin has anti-tumor, antioxidant and anti-inflammatory effects. Fraxetin induces apoptosis. |
| EINECS | 209-376-2 |
| HTC | 2932209090 |
| PubChem ID | 24855272 |
| MDL Number | MFCD00006873 |
| SMILES | COc1cc2C=CC(=O)Oc2c(O)c1O |
| InChI | 1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3 |
| InChI Key | HAVWRBANWNTOJX-UHFFFAOYSA-N |
| NACRES Code | NA.23 |
| UNSPSC | 12162002 |
| MSDS | msds/22994_1_574_84_5.pdf |
| Use of | Fraxetin is isolated from Cortex Fraxini. Fraxetin has antitumor, anti-oxidation effects and anti-inflammory effects. Fraxetin induces apoptosis[1]. Properties Articles14 Name 7,8-dihydroxy-6-methoxychromen-2-one Synonym More Synonyms Fraxetin Biological Activity Description Fraxetin is isolated from Cortex Fraxini. Fraxetin has antitumor, anti-oxidation effects and anti-inflammory effects. Fraxetin induces apoptosis[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis References [1]. Chen X, et al. The therapeutic effect of fraxetin on ethanol-induced hepatic fibrosis by enhancing ethanol metabolism, inhibiting oxidative stress and modulating inflammatory mediators in rats. Int Immunopharmacol. 2018 Mar;56:98-104. [2]. Liu G, et al. Effect of fraxetin on proliferation and apoptosis in breast cancer cells. Oncol Lett. 2017 Dec;14(6):7374-7378. Chemical & Physical Properties Molecular Formula C10H8O5 Exact Mass 208.037170 PSA 79.90000 Index of Refraction 1.648 InChIKey HAVWRBANWNTOJX-UHFFFAOYSA-N Safety Information Signal Word Warning Hazard Statements H302 + H312 + H332-H315-H319-H335 Precautionary Statements P261-P280-P305 + P351 + P338 Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves Hazard Codes Xn: Harmful; Safety Phrases S26-S36 RIDADR NONH for all modes of transport HS Code 2932209090 Precursor & DownStream Precursor 8 CAS#:73815-12-0 fraxetin diacetate CAS#:4055-69-0 2,3-dihydroxy-4... CAS#:71765-80-5 6-Methoxy-7-(3-... CAS#:77369-04-1 DownStream 6 CAS#:486-21-5 Isofraxidin CAS#:525-21-3 CAS#:28843-40-5 7,8-METHYLENEDI... CAS#:6035-49-0 6,7,8-Trimethox... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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