CAS Number537-98-4
SynonymsConiferic acid; (E)-4-Hydroxy-3-methoxycinnamic acid; Metronidazole Benzoate; trans-4-Hydroxy-3-methoxycinnamic acid,trans-Ferulic acid,Ferulic acid; (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid; 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylic acid; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-, benzoate (ester); MFCD00004400; trans-4-Hydroxy-3-methoxycinnamic acid,Ferulic acid; (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid; caffeic acid 3-methyl ether; Benzoylmetronildazole; (E)-4-hydroxy-3-methoxy-Cinnamic acid; (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; Trans-4-Hydroxy-3-methoxycinnamic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid; (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-prop
Molecular FormulaHOC6H3(OCH3)CH=CHCO2H
Molecular Weight194.18
Purity99%
Density1.3±0.1 g/cm3
Boiling Point372.3±27.0 °C at 760 mmHg
Melting Point168-172 °C (lit.)
Appearancepowder
EINECS208-679-7
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 537-98-4 |
| Catalog No. | 2A-9022697 |
| Chinese Name | 反式阿魏酸 |
| Synonyms | Coniferic acid; (E)-4-Hydroxy-3-methoxycinnamic acid; Metronidazole Benzoate; trans-4-Hydroxy-3-methoxycinnamic acid,trans-Ferulic acid,Ferulic acid; (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid; 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylic acid; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-, benzoate (ester); MFCD00004400; trans-4-Hydroxy-3-methoxycinnamic acid,Ferulic acid; (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid; caffeic acid 3-methyl ether; Benzoylmetronildazole; (E)-4-hydroxy-3-methoxy-Cinnamic acid; (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; Trans-4-Hydroxy-3-methoxycinnamic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid; (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-prop |
| Molecular Formula | HOC6H3(OCH3)CH=CHCO2H |
| Molecular Weight | 194.18 |
| Purity | 99 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 372.3±27.0 °C at 760 mmHg |
| Melting Point | 168-172 °C (lit.) |
| Appearance | powder |
| Water Solubility | Soluble in: methanol |
| Storage Condition | Store sealed and placed in a ventilated, dry place |
| Application | (E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin, leading to proteasomal degradation, increasing t |
| EINECS | 208-679-7 |
| PubChem ID | 24847872 |
| MDL Number | MFCD00004400 |
| SMILES | OC(/C=C/C1=CC(OC)=C(O)C=C1)=O |
| InChI | 1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| InChI Key | KSEBMYQBYZTDHS-HWKANZROSA-N |
| Beilstein/REAXYS | 1570363 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/22697_1_537_98_4.pdf |
| Bioactivity | (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Related Catalog Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer Target Bax References [1]. Fong Y, et al. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med. 2016 Oct 1;11:45. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 372.3±27.0 °C at 760 mmHg Melting Point 168-172ºC Molecular Formula C10H10O4 Molecular Weight 194.184 Flash Point 150.5±17.2 °C Exact Mass 194.057907 PSA 66.76000 LogP 1.64 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.627 InChIKey KSEBMYQBYZTDHS-HWKANZROSA-N SMILES COc1cc(C=CC(=O)O)ccc1O Stability Stable. Incompatible with strong oxidizing agents. |
| Use of | (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Properties Articles234 Name Trans-Ferulic Acid Synonym More Synonyms (E)-Ferulic acid Biological Activity Description (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Related Catalog Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer References [1]. Fong Y, et al. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med. 2016 Oct 1;11:45. Chemical & Physical Properties Molecular Formula C10H10O4 Exact Mass 194.057907 PSA 66.76000 Index of Refraction 1.627 InChIKey KSEBMYQBYZTDHS-HWKANZROSA-N Stability Stable. Incompatible with strong oxidizing agents. |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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