CAS Number67-97-0
SynonymsOxarol; Vitamin D3; Ebivit; Cholecalciferolum; (3S,5Z,7E)-9,10-Secocholesta-5,7,10-trien-3-ol; Micro-Dee; (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol; Deparal; FeraCol; MFCD00078131; Prezios; cholecalciferol; Vi-De3; MC 1275; Granuvit D3; Devaron; (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; rampage; vitamin D3 powder; D3-Vicotrat; NEO Dohyfral D3; Vigantol; EINECS 200-673-2; colecalciferol; Videkhol; (3β,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; [3H]-Vitamin D3; 9,10-Secocholesta-5,7,10(19)-trien-3b-ol; calciol; Provitina
Molecular FormulaC27H44O
Molecular Weight384.64
Purity98%
Density1.0±0.1 g/cm3
Boiling Point496.4±24.0 °C at 760 mmHg
Melting Point83-86 °C (lit.)
Appearancesolid
EINECS200-673-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 67-97-0 |
| Catalog No. | 2A-0200198 |
| Chinese Name | 维生素D3 |
| Synonyms | Oxarol; Vitamin D3; Ebivit; Cholecalciferolum; (3S,5Z,7E)-9,10-Secocholesta-5,7,10-trien-3-ol; Micro-Dee; (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol; Deparal; FeraCol; MFCD00078131; Prezios; cholecalciferol; Vi-De3; MC 1275; Granuvit D3; Devaron; (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; rampage; vitamin D3 powder; D3-Vicotrat; NEO Dohyfral D3; Vigantol; EINECS 200-673-2; colecalciferol; Videkhol; (3β,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; [3H]-Vitamin D3; 9,10-Secocholesta-5,7,10(19)-trien-3b-ol; calciol; Provitina |
| Molecular Formula | C27H44O |
| Molecular Weight | 384.64 |
| Purity | 98 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 496.4±24.0 °C at 760 mmHg |
| Melting Point | 83-86 °C (lit.) |
| Appearance | solid |
| Storage Condition | 3. This product should be sealed and stored in a c |
| Packaging | II |
| Application | Cholecalciferol (Vitamin D3) is a naturally occurring form of vitamin D that can induce cell differentiation and cancer cell proliferation after metabolic activation. |
| EINECS | 200-673-2 |
| HTC | 2936240000 |
| UN(IATA) | UN 2811 |
| PubChem ID | 329823242 |
| MDL Number | MFCD00078131 |
| SMILES | CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C |
| InChI | 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1 |
| InChI Key | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| Beilstein/REAXYS | 2339331 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 6.1 |
| Risk Codes | R24/25;R26;R48/25 |
| Safety Description | S28A;S36/37;S45 |
| MSDS | msds/8907_1_67_97_0.pdf |
| Bioactivity | Cholecalciferol(Vitamin D3) is a naturally occuring form of vitamin D; Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. IC50 value:Target: Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis. Related Catalog Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Cancer Natural Products >> Others Target Human Endogenous Metabolite References [1]. Leibowitz SB, Kantoff PW. Differentiating agents and the treatment of prostate cancer: Vitamin D3 and peroxisome proliferator-activated receptor gamma ligands. Semin Oncol. 2003 Oct;30(5):698-708. [2]. Di Rosa M, Malaguarnera M, Nicoletti F, Malaguarnera L. Vitamin D3: a helpful immuno-modulator. Immunology. 2011 Oct;134(2):123-39. doi: 10.1111/j.1365-2567.2011.03482.x. [3]. Krishnan AV, Feldman D. Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D. Annu Rev Pharmacol Toxicol. 2011;51:311-36. doi: 10.1146/annurev-pharmtox-010510-100611. [4]. Nigwekar SU, Bhan I, Thadhani R. Ergocalciferol and cholecalciferol in CKD. Am J Kidney Dis. 2012 Jul;60(1):139-56. doi: 10.1053/j.ajkd.2011.12.035. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 496.4±24.0 °C at 760 mmHg Melting Point 83-86 °C(lit.) Molecular Formula C27H44O Molecular Weight 384.638 Flash Point 214.2±15.1 °C Exact Mass 384.339203 PSA 20.23000 LogP 9.72 Vapour Pressure 0.0±2.9 mmHg at 25°C Index of Refraction 1.523 Storage condition 2~8°C |
| Use of | Cholecalciferol(Vitamin D3) is a naturally occuring form of vitamin D; Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. IC50 value:Target: Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis. Properties Articles228 Name calciol Synonym More Synonyms Vitamin D3 Biological Activity Description Cholecalciferol(Vitamin D3) is a naturally occuring form of vitamin D; Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. IC50 value:Target: Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis. Related Catalog Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Cancer Natural Products >> Others Human Endogenous Metabolite References [1]. Leibowitz SB, Kantoff PW. Differentiating agents and the treatment of prostate cancer: Vitamin D3 and peroxisome proliferator-activated receptor gamma ligands. Semin Oncol. 2003 Oct;30(5):698-708. Chemical & Physical Properties Molecular Formula C27H44O Exact Mass 384.339203 PSA 20.23000 Index of Refraction 1.523 |
| Transport Info | Product name: Vitamin D3 |
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