CAS Number41468-25-1
SynonymsPyridoxal 5'-phosphate monohydrate; 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-, hydrate (1:1); (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate (1:1); 5-Phosphate Monohydrate; PYRIDOXAL-5-PHOSPHATE H2O; EINECS 200-208-3; phosphopyridoxalmonohydrate; MFCD00149414; (4-Formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl dihydrogen phosphate hydrate (1:1); Pyridoxal 5-phosphate; Codecarboxylase Monohydrate; 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde; pyridoxylphosphatemonohydrate; PLP; PYRIDOXAL-5-PHOSPHATEextrapure; Pyridoxal 5-Phosphate Monohydrate; Codecarboxylase
Molecular FormulaC8H12NO7P
Molecular Weight265.16
Purity≥97.0 (NT)%
Boiling Point565.7ºC at 760 mmHg
Melting Point140-143 °C (lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 41468-25-1 |
| Catalog No. | 2A-9008716 |
| Chinese Name | 5-磷酸吡哆醛 |
| Synonyms | Pyridoxal 5'-phosphate monohydrate; 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-, hydrate (1:1); (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate (1:1); 5-Phosphate Monohydrate; PYRIDOXAL-5-PHOSPHATE H2O; EINECS 200-208-3; phosphopyridoxalmonohydrate; MFCD00149414; (4-Formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl dihydrogen phosphate hydrate (1:1); Pyridoxal 5-phosphate; Codecarboxylase Monohydrate; 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde; pyridoxylphosphatemonohydrate; PLP; PYRIDOXAL-5-PHOSPHATEextrapure; Pyridoxal 5-Phosphate Monohydrate; Codecarboxylase |
| Molecular Formula | C8H12NO7P |
| Molecular Weight | 265.16 |
| Purity | ≥97.0 (NT) |
| Boiling Point | 565.7ºC at 760 mmHg |
| Melting Point | 140-143 °C (lit.) |
| Appearance | powder |
| Water Solubility | 5 g/L (20 ºC) |
| Storage Condition | This product should be sealed and stored in a dry |
| Application | Pyridoxal 5'-phosphate hydrate is the active form of vitamin B6, which is an important cofactor for several enzymes, including aromatic L-amino acid decarboxylase, which catalyzes the final stages of |
| HTC | 2936250000 |
| PubChem ID | 57652935 |
| MDL Number | MFCD00149414 |
| SMILES | O=CC1=C(C(C)=NC=C1COP(O)(O)=O)O.[OH] |
| InChI | 1S/C8H10NO6P.H2O/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14;/h2-3,11H,4H2,1H3,(H2,12,13,14);1H2 |
| InChI Key | CEEQUQSGVRRXQI-UHFFFAOYSA-N |
| Beilstein/REAXYS | 234749 |
| NACRES Code | NA.51 |
| UNSPSC | 12352204 |
| Hazard Symbols | Transport |
| Safety Description | S24/25 |
| MSDS | msds/8716_2_41468_25_1.pdf |
| Bioactivity | Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others Target IC50: active form of vitamin B6[1] References [1]. Allen GF, et al. Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.J Neurochem. 2010 Jul;114(1):87-96. [2]. Calderón-Ospina CA, et al. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.CNS Neurosci Ther. 2020 Jan;26(1):5-13. Chemical & Physical Properties Boiling Point 565.7ºC at 760 mmHg Melting Point 140-143 °C(lit.) Molecular Formula C8H12NO7P Molecular Weight 265.157 Flash Point 296ºC Exact Mass 265.035126 PSA 135.99000 LogP 0.45310 InChIKey CEEQUQSGVRRXQI-UHFFFAOYSA-N SMILES Cc1ncc(COP(=O)(O)O)c(C=O)c1O.O Storage condition 2-8°C Water Solubility 5 g/L (20 ºC) |
| Use of | Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2]. Properties Articles74 Name Pyridoxal 5'-phosphate Synonym More Synonyms Pyridoxal 5'-phosphate monohydrate Biological Activity Description Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others IC50: active form of vitamin B6[1] References [1]. Allen GF, et al. Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.J Neurochem. 2010 Jul;114(1):87-96. [2]. Calderón-Ospina CA, et al. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.CNS Neurosci Ther. 2020 Jan;26(1):5-13. Chemical & Physical Properties Molecular Formula C8H12NO7P Exact Mass 265.035126 PSA 135.99000 LogP 0.45310 InChIKey CEEQUQSGVRRXQI-UHFFFAOYSA-N SMILES Cc1ncc(COP(=O)(O)O)c(C=O)c1O.O |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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