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Home > Products > Pharmaceutical R&D Materials > Functional Building Blocks > (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid structure, CAS 1072833-77-2

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

CAS Number1072833-77-2

SynonymsB-{(1R)-1-[2-(2,5-dichlorobenzamido)acetamido]-3-methylbutyl}boronic acid; N-(2,5-Dichlorobenzoyl)-N-[(1R)-1-(dihydroxyboryl)-3-methylbutyl]glycinamide; [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methyl-butyl]boronic acid; MLN2238; ixazomib; Ixazomib; B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid

Molecular FormulaC14H19BCl2N2O4

Molecular Weight361.029

Purity

Density1.3±0.1 g/cm3

Boiling Point

Melting Point

Flash Point

Appearance

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Cat. No.: 2A-1170245 Purity:
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Quality Control of [ 1072833-77-2 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1072833-77-2
Catalog No.2A-1170245
Chinese Name艾沙佐米
SynonymsB-{(1R)-1-[2-(2,5-dichlorobenzamido)acetamido]-3-methylbutyl}boronic acid; N-(2,5-Dichlorobenzoyl)-N-[(1R)-1-(dihydroxyboryl)-3-methylbutyl]glycinamide; [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methyl-butyl]boronic acid; MLN2238; ixazomib; Ixazomib; B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
Molecular FormulaC14H19BCl2N2O4
Molecular Weight361.029
Density1.3±0.1 g/cm3
Storage Condition2-8°C
ApplicationIxazomib (MLN2238) is a potent and selective reversible proteasome inhibitor that inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM and a Ki of 0.93 nM.
PubChem ID57291607
SMILESCC(C)CC(NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O
InChIInChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1
InChI KeyMXAYKZJJDUDWDS-LBPRGKRZSA-N
Transport InfoProduct name: MLN2238
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