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AZD 1080

Name: AZD 1080
Brand: 2A Biotech
SKU: 2A-1170191

CAS Number612487-72-6

Synonyms2-Hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-1H-indole-5-carbonitrile; 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile; 1H-INDOLE-5-CARBONITRILE,2-HYDROXY-3-[5-(4-MORPHOLINYLMETHYL)-2-PYRIDINYL]; Kinome_2945; AZD1080

Molecular FormulaC19H18N4O2

Molecular Weight334.372

Density1.4±0.1 g/cm3

Boiling Point594.0±50.0 °C at 760 mmHg

MSDSChinese English

Cat. No.: 2A-1170191 Purity:

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Quality Control of [ 612487-72-6 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	612487-72-6
Catalog No.	2A-1170191
Chinese Name	2-羟基-3-[5-(吗啉-4-甲基)吡啶-2-基]-1H-吲哚-5-甲腈
Synonyms	2-Hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-1H-indole-5-carbonitrile; 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile; 1H-INDOLE-5-CARBONITRILE,2-HYDROXY-3-[5-(4-MORPHOLINYLMETHYL)-2-PYRIDINYL]; Kinome_2945; AZD1080
Molecular Formula	C19H18N4O2
Molecular Weight	334.372
Density	1.4±0.1 g/cm3
Boiling Point	594.0±50.0 °C at 760 mmHg
Storage Condition	-20°C
Application	AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3α and GSK3β,pKi with IC50 of 8.2 (6.9 nM) and 7.5 (31 nM), respectively.
SMILES	N#Cc1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1
InChI	InChI=1S/C19H18N4O2/c20-10-13-1-3-16-15(9-13)18(19(24)22-16)17-4-2-14(11-21-17)12-23-5-7-25-8-6-23/h1-4,9,11,22,24H,5-8,12H2
InChI Key	BLTVBQXJFVRPFK-UHFFFAOYSA-N
Transport Info	Product name: AZD1080

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AZD 1080

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