RKI1447

Name: RKI1447
Brand: 2A Biotech
SKU: 2A-1170196

CAS Number1342278-01-6

Synonyms1-(3-Hydroxybenzyl)-3-[4-(4-pyridinyl)-1,3-thiazol-2-yl]urea; FD5032; RKI-1447; 1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea; 07R

Molecular FormulaC16H14N4O2S

Molecular Weight326.373

Density1.4±0.1 g/cm3

Cat. No.: 2A-1170196 Purity:

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Quality Control of [ 1342278-01-6 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1342278-01-6
Catalog No.	2A-1170196
Chinese Name	1-(3-羟基苄基)-3-[4-(吡啶-4-基)噻唑-2-基]脲
Synonyms	1-(3-Hydroxybenzyl)-3-[4-(4-pyridinyl)-1,3-thiazol-2-yl]urea; FD5032; RKI-1447; 1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea; 07R
Molecular Formula	C16H14N4O2S
Molecular Weight	326.373
Density	1.4±0.1 g/cm3
Storage Condition	-20°C
Application	RKI-1447 is a highly effective small molecule inhibitor of ROCK1 and ROCK2, with IC50 values of 14.5 nM and 6.2 nM respectively.
PubChem ID	143472448
SMILES	O=C(NCc1cccc(O)c1)Nc1nc(-c2ccncc2)cs1
InChI	InChI=1S/C16H14N4O2S/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12/h1-8,10,21H,9H2,(H2,18,19,20,22)
InChI Key	GDVRVPIXWXOKQO-UHFFFAOYSA-N
Transport Info	Product name: RKI-1447

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