
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 945755-56-6 |
| Catalog No. | 2A-1170195 |
| Chinese Name | (2S)-N-[4-[2-[[4-(4-吗啉基)苯基]氨基]-4-嘧啶基]苯基]-2-吡咯烷甲酰胺 |
| Synonyms | s7036; N-[4-(2-{[4-(4-Morpholinyl)phenyl]amino}-4-pyrimidinyl)phenyl]-L-prolinamide; xl019 |
| Molecular Formula | C25H28N6O2 |
| Molecular Weight | 444.529 |
| Density | 1.3±0.1 g/cm3 |
| Appearance | light yellow solid |
| Storage Condition | -20℃ |
| Application | XL019 is a JAK2 selective inhibitor with an IC50 of 2.2 nM, which is 100 times more potent than JAK1. It has good molecular biology and cellular activity. |
| PubChem ID | 138051907 |
| SMILES | O=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)C1CCCN1 |
| InChI | InChI=1S/C25H28N6O2/c32-24(23-2-1-12-26-23)28-19-5-3-18(4-6-19)22-11-13-27-25(30-22)29-20-7-9-21(10-8-20)31-14-16-33-17-15-31/h3-11,13,23,26H,1-2,12,14-17H2,(H,28,32)(H,27,29,30)/t23-/m0/s1 |
| InChI Key | ISOCDPQFIXDIMS-QHCPKHFHSA-N |
| Transport Info | Product name: XL019 |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| RGFP-966 | 1357389-11-7 | 2A-1170190 |
| AZD 1080 | 612487-72-6 | 2A-1170191 |
| SKLB 610 | 1125780-41-7 | 2A-1170192 |
| XL-765,SAR245409 | 1123889-87-1 | 2A-1170193 |
| XL765 | 1349796-36-6 | 2A-1170194 |
| RKI1447 | 1342278-01-6 | 2A-1170196 |
| SB1317 | 937270-47-8 | 2A-1170197 |
| JAK INHIBITOR I | 457081-03-7 | 2A-1170198 |
| NSC 42834 | 195371-52-9 | 2A-1170199 |
| LDN-211904 | 1198408-39-7 | 2A-1170201 |
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