XL019 structure, CAS 945755-56-6

XL019

CAS Number945755-56-6

Synonymss7036; N-[4-(2-{[4-(4-Morpholinyl)phenyl]amino}-4-pyrimidinyl)phenyl]-L-prolinamide; xl019

Molecular FormulaC25H28N6O2

Molecular Weight444.529

Purity

Density1.3±0.1 g/cm3

Boiling Point

Melting Point

Flash Point

Appearancelight yellow solid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-1170195 Purity:
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Quality Control of [ 945755-56-6 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number945755-56-6
Catalog No.2A-1170195
Chinese Name(2S)-N-[4-[2-[[4-(4-吗啉基)苯基]氨基]-4-嘧啶基]苯基]-2-吡咯烷甲酰胺
Synonymss7036; N-[4-(2-{[4-(4-Morpholinyl)phenyl]amino}-4-pyrimidinyl)phenyl]-L-prolinamide; xl019
Molecular FormulaC25H28N6O2
Molecular Weight444.529
Density1.3±0.1 g/cm3
Appearancelight yellow solid
Storage Condition-20℃
ApplicationXL019 is a JAK2 selective inhibitor with an IC50 of 2.2 nM, which is 100 times more potent than JAK1. It has good molecular biology and cellular activity.
PubChem ID138051907
SMILESO=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)C1CCCN1
InChIInChI=1S/C25H28N6O2/c32-24(23-2-1-12-26-23)28-19-5-3-18(4-6-19)22-11-13-27-25(30-22)29-20-7-9-21(10-8-20)31-14-16-33-17-15-31/h3-11,13,23,26H,1-2,12,14-17H2,(H,28,32)(H,27,29,30)/t23-/m0/s1
InChI KeyISOCDPQFIXDIMS-QHCPKHFHSA-N
Transport InfoProduct name: XL019
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