
CAS Number1357389-11-7
SynonymsBenzenamine,N-[1-(2-phenylethenyl)pentyl]; (2E)-N-(2-Amino-4-fluorophenyl)-3-{1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl}acrylamide; (E)-N-(1-phenylhept-1-en-3-yl)aniline; (E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide; RGFP 966; RGFP966
Molecular FormulaC21H19FN4O
Molecular Weight362.400
Density1.2±0.1 g/cm3
Boiling Point630.4±55.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1357389-11-7 |
| Catalog No. | 2A-1170190 |
| Chinese Name | RGFP966 |
| Synonyms | Benzenamine,N-[1-(2-phenylethenyl)pentyl]; (2E)-N-(2-Amino-4-fluorophenyl)-3-{1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl}acrylamide; (E)-N-(1-phenylhept-1-en-3-yl)aniline; (E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide; RGFP 966; RGFP966 |
| Molecular Formula | C21H19FN4O |
| Molecular Weight | 362.400 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 630.4±55.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | RGFP966 is a highly selective HDAC3 inhibitor with an IC50 of 80 nM. No inhibitory effect on other HDACs at 15 μM. |
| PubChem ID | 85734935 |
| SMILES | Nc1cc(F)ccc1NC(=O)C=Cc1cnn(CC=Cc2ccccc2)c1 |
| InChI | InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11,13-15H,12,23H2,(H,25,27)/b7-4+,11-8+ |
| InChI Key | BLVQHYHDYFTPDV-VCABWLAWSA-N |
| Transport Info | Product name: RGFP966 |
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