CAS Number67-96-9
SynonymsDihydrotachysterin2; AT-10; ANTITANIL; Dygrayl; parterol; MFCD00867069; dygratyl; Tachyrol; DIHYDROTACHYSTEROL; dihydral; dht2; EINECS 200-672-7
Molecular FormulaC28H46O
Molecular Weight398.66
Purity≥98%
Density1.003 g/cm3
Boiling Point499.5ºC at 760 mmHg
Melting Point131ºC
Appearancesolid
EINECS200-672-7
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 67-96-9 |
| Catalog No. | 2A-9016963 |
| Chinese Name | 多沙唑嗪杂质F |
| Synonyms | Dihydrotachysterin2; AT-10; ANTITANIL; Dygrayl; parterol; MFCD00867069; dygratyl; Tachyrol; DIHYDROTACHYSTEROL; dihydral; dht2; EINECS 200-672-7 |
| Molecular Formula | C28H46O |
| Molecular Weight | 398.66 |
| Purity | ≥98 |
| Density | 1.003 g/cm3 |
| Boiling Point | 499.5ºC at 760 mmHg |
| Melting Point | 131ºC |
| Appearance | solid |
| Storage Condition | -20°C |
| Packaging | III |
| Application | Dihydrotachycardia is a synthetic analog of vitamin D. Dihydrotachycardia can be used to study hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the bo |
| EINECS | 200-672-7 |
| PubChem ID | 24894275 |
| SMILES | C[C@@H]([C@@]1([H])CC[C@@]2([H])/C(CCC[C@@]21C)=C/C=C3[C@@H](C)CC[C@H](O)C/3)/C=C/[C@H](C)C(C)C |
| InChI | 1S/C28H46O/c1-19(2)20(3)12-13-22(5)25-16-17-26-23(10-8-18-28(25,26)6)14-15-24-21(4)9-7-11-27(24)29/h12-15,19-22,25-27,29H,7-11,16-18H2,1-6H3/b13-12+,23-14+,24-15+/t20-,21-,22+,25?,26?,27-,28+/m0/s1 |
| InChI Key | DTSXXSAWQHPLEF-GFVAUXBKSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/16963_1_67_96_9.pdf |
| Bioactivity | Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [1][2]. Related Catalog Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Metabolic Disease In Vitro Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue[1]. Dihydrotachysterol also increases renal phosphate excretion[1]. In Vivo Dihydrotachysterol is a potent synthetic vitamin D analogue that is widely available but more expensive than vitamin D2. It has an onset of action and half-life between those of vitamin D2 and calcitriol. Dihydrotachysterol (initially given at 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosages range from 0.004 to 0.04 mg/kg/day) is useful for the treatment of hypoparathyroidism[2]. Animal Model: Animal Model: Five young to middle-aged cats of mixed breeding[2] Dosage: Initially given at a dosage ranging from 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosage ranged from 0.004 to 0.04 mg/kg/day. Administration: Oral administration Result: Was useful for the treatment of hypoparathyroidism. References [1]. I Quack, et al. Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate monitoring. Five cases and a review. Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):376-80. [2]. M E Peterson, et al. Idiopathic hypoparathyroidism in five cats. J Vet Intern Med. Jan-Feb 1991;5(1):47-51. Chemical & Physical Properties Density 1.003 g/cm3 Boiling Point 499.5ºC at 760 mmHg Melting Point 131ºC Molecular Formula C28H46O Molecular Weight 398.66400 Flash Point 217.6ºC Exact Mass 398.35500 PSA 20.23000 LogP 7.72090 Index of Refraction 1.569 InChIKey ILYCWAKSDCYMBB-UHFFFAOYSA-N SMILES CC1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)C=CC(C)C(C)C Storage condition -20°C |
| Use of | Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [1][2]. Properties Articles26 Name dihydrotachysterol Synonym More Synonyms HSDB 3314 Biological Activity Description Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [1][2]. Related Catalog Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Metabolic Disease In Vitro Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue[1]. Dihydrotachysterol also increases renal phosphate excretion[1]. References [1]. I Quack, et al. Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate monitoring. Five cases and a review. Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):376-80. [2]. M E Peterson, et al. Idiopathic hypoparathyroidism in five cats. J Vet Intern Med. Jan-Feb 1991;5(1):47-51. Chemical & Physical Properties Molecular Formula C28H46O Exact Mass 398.35500 PSA 20.23000 LogP 7.72090 Index of Refraction 1.569 InChIKey ILYCWAKSDCYMBB-UHFFFAOYSA-N |
| Transport Info | Product name: Dihydrotachysterol |
| Related Products in Botanical Reference Standards | ||
|---|---|---|
| 4,4-Dinitrostilbene-2,2-Disulphonic acid | 128-42-7 | 2A-9013471 |
| Anthraquinone | 84-65-1 | 2A-9013732 |
| Anthraquinone-1,5-disulfonic acid | 117-14-6 | 2A-9013733 |
| Gallic acid | 149-91-7 | 2A-9014493 |
| Tannic acid | 1401-55-4 | 2A-9015839 |
| 1,2-Dihydroxy anthraquinone | 72-48-0 | 2A-9017031 |
| Dihydrocholesterol | 80-97-7 | 2A-9017326 |
| 1,8-Dihydroxy-4,5-dinitroanthraquinone | 81-55-0 | 2A-9017349 |
| 1,4,5,8-Tetrachloroanthraquinone | 81-58-3 | 2A-9017350 |
| 1-Amino-4-bromo anthraquinone | 81-62-9 | 2A-9017351 |
| Browse all Botanical Reference Standards products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS