CAS Number175865-60-8
SynonymsL-Valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester; 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl L-Valinate; Valcyte; Cymeval; valganciclovir; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl L-valinate; L-Valine, 2-[(2-amino-3,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester; valgancyclovir
Molecular FormulaC14H22N6O5
Molecular Weight390.82 (anhydrous basis)
Purity98.00%
Density1.6±0.1 g/cm3
Boiling Point629.1±65.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 175865-60-8 |
| Catalog No. | 2A-9012903 |
| Chinese Name | 缬更昔洛韦 |
| Synonyms | L-Valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester; 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl L-Valinate; Valcyte; Cymeval; valganciclovir; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl L-valinate; L-Valine, 2-[(2-amino-3,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester; valgancyclovir |
| Molecular Formula | C14H22N6O5 |
| Molecular Weight | 390.82 (anhydrous basis) |
| Purity | 98.00 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 629.1±65.0 °C at 760 mmHg |
| Storage Condition | Room temperature, dry |
| Application | Valganciclovir is the original drug of ganciclovir and has activity against CMV infection. |
| HTC | 2933990090 |
| SMILES | O.Cl.CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2C(=O)N=C(N)Nc12 |
| InChI | 1S/C14H22N6O5.ClH.H2O/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H;1H2/t8?,9-;;/m0../s1 |
| InChI Key | XASVRRIYQZVANH-AHBBCRTASA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/12903_1_175865_60_8.pdf |
| Use of | Properties Name valganciclovir Synonym More Synonyms Valganciclovir Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> CMV Research Areas >> Infection References [1]. Sugawara M, et al. Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J Pharm Sci. 2000 Jun;89(6):781-9. [2]. Chawla JS, et al. Oral valganciclovir versus ganciclovir as delayed pre-emptive therapy for patients after allogeneic hematopoietic stem cell transplant: a pilot trial (04-0274) and review of the literature. Transpl Infect Dis. 2012 Jun;14(3):259-67. [3]. O'Brien S, et al. Valganciclovir prevents cytomegalovirus reactivation in patients receiving alemtuzumab-based therapy. Blood. 2008 Feb 15;111(4):1816-9. Chemical & Physical Properties Molecular Formula C14H22N6O5 Exact Mass 354.165161 PSA 171.37000 LogP -1.28 Index of Refraction 1.678 InChIKey WPVFJKSGQUFQAP-UHFFFAOYSA-N Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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