| Chemical & Physical Properties | |
|---|---|
| CAS Number | 112811-59-3 |
| Catalog No. | 2A-9012631 |
| Chinese Name | 加替沙星 |
| Synonyms | Tequin; Zymar; Gatifloxacin; MFCD00895399; Zymaxid; Gatiflo |
| Molecular Formula | C19H22FN3O4 |
| Molecular Weight | 375.39 |
| Purity | 99 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 607.8±55.0 °C at 760 mmHg |
| Melting Point | 162°C |
| Appearance | white powder |
| Storage Condition | Store at 0-5°C |
| Application | Gatifloxacin is a fourth-generation fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. |
| HTC | 2933990090 |
| PubChem ID | 329749928 |
| SMILES | COc1c(N2CCNC(C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 |
| InChI | InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) |
| InChI Key | XUBOMFCQGDBHNK-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/12631_1_112811_59_3.pdf |
| Use of | Properties Name gatifloxacin Synonym More Synonyms Gatifloxacin Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Fukuda, H., S. Hori, and K. Hiramatsu, Antibacterial activity of gatifloxacin (AM-1155, CG5501, BMS-206584), a newly developed fluoroquinolone, against sequentially acquired quinolone-resistant mutants and the norA transformant of Staphylococcus aureus. A [2]. Jensen, H., et al., Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits. J Ocul Pharmacol Ther, 2005. 21(1): p. 36-43. [3]. Cheung, O., et al., Gatifloxacin-induced hepatotoxicity and acute pancreatitis. Ann Intern Med, 2004. 140(1): p. 73-4. [4]. Fteha, A., et al., Gatifloxacin induced torsades de pointes. Pacing Clin Electrophysiol, 2004. 27(10): p. 1449-50. Chemical & Physical Properties Molecular Formula C19H22FN3O4 Exact Mass 375.159424 PSA 83.80000 Index of Refraction 1.616 InChIKey XUBOMFCQGDBHNK-UHFFFAOYSA-N Safety Information Hazard Codes Xn RTECS BT1750000 HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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