CAS Number23288-49-5
Synonyms4,4'-(Isopropylidenedithio)bis[2,6-di-tert-butylphenol]; Biphenabid; Lursell; EINECS 245-560-9; Probucol; 2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol; Acetone Bis(3,5-di-tert-butyl-4-hydroxyphenyl)mercaptole; Bisbid; Panavir; Sinlestal; Lurselle; 4,4'-((1-methylethylidene)-bis(thio))-bis(2,6-bis(1,1-dimethylethyl)phenol); 4,4'-[(1-methylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol]; 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol); 4,4'-[(1-Methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol]; Probucolum; MFCD00079281; Lesterol; Lorelco; Bisphenabid; 4,4'-(isopropylidenedithio)-bis-(2,6-di-tert-butylphenol); 4,4'-(2,2-Propanediyldisulfanediyl)bis[2,6-bis(2-methyl-2-propanyl)phenol]
Molecular FormulaC31H48O2S2
Molecular Weight516.84
Purity98%
Density1.1±0.1 g/cm3
Boiling Point546.7±50.0 °C at 760 mmHg
Melting Point117 118ºC
Appearancewhite solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 23288-49-5 |
| Catalog No. | 2A-9012128 |
| Chinese Name | 丙丁酚 |
| Synonyms | 4,4'-(Isopropylidenedithio)bis[2,6-di-tert-butylphenol]; Biphenabid; Lursell; EINECS 245-560-9; Probucol; 2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol; Acetone Bis(3,5-di-tert-butyl-4-hydroxyphenyl)mercaptole; Bisbid; Panavir; Sinlestal; Lurselle; 4,4'-((1-methylethylidene)-bis(thio))-bis(2,6-bis(1,1-dimethylethyl)phenol); 4,4'-[(1-methylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol]; 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol); 4,4'-[(1-Methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol]; Probucolum; MFCD00079281; Lesterol; Lorelco; Bisphenabid; 4,4'-(isopropylidenedithio)-bis-(2,6-di-tert-butylphenol); 4,4'-(2,2-Propanediyldisulfanediyl)bis[2,6-bis(2-methyl-2-propanyl)phenol] |
| Molecular Formula | C31H48O2S2 |
| Molecular Weight | 516.84 |
| Purity | 98 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 546.7±50.0 °C at 760 mmHg |
| Melting Point | 117 118ºC |
| Appearance | white solid |
| Water Solubility | Water solubility: insoluble; soluble in: acetone, |
| Storage Condition | Store in a compact container in a cool, dry place |
| Application | Probucol can fight hyperlipidemia and reduce blood cholesterol levels by increasing the metabolic rate of LDL. |
| HTC | 29093090 |
| MDL Number | MFCD00079281 |
| SMILES | CC(C)(C)c1cc(SC(C)(C)Sc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C |
| InChI | 1S/C31H48O2S2/c1-27(2,3)21-15-19(16-22(25(21)32)28(4,5)6)34-31(13,14)35-20-17-23(29(7,8)9)26(33)24(18-20)30(10,11)12/h15-18,32-33H,1-14H3 |
| InChI Key | FYPMFJGVHOHGLL-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/12128_1_23288_49_5.pdf |
| Bioactivity | Probucol is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.Target: OthersProbucol is a drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. Probucol inhibited cholesterol efflux up to 80% in J774 macrophages expressing ABCA1. probucol is an effective inhibitor of ABCA1-mediated cholesterol efflux without influencing scavenger receptor class B type I-mediated efflux. The inhibition of ABCA1 translocation to the plasma membrane may in part explain the reported in vivo high-density lipoprotein-lowering action of probucol [1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Phenols References [1]. Probucol Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 546.7±50.0 °C at 760 mmHg Melting Point 117 118ºC Molecular Formula C31H48O2S2 Molecular Weight 516.842 Flash Point 264.9±28.8 °C Exact Mass 516.309570 PSA 91.06000 LogP 10.27 Vapour Pressure 0.0±1.5 mmHg at 25°C Index of Refraction 1.574 InChIKey FYPMFJGVHOHGLL-UHFFFAOYSA-N SMILES CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 Storage condition Desiccate at +4°C |
| Use of | Properties Articles62 Name probucol Synonym More Synonyms Probucol Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Phenols References [1]. Probucol Chemical & Physical Properties Molecular Formula C31H48O2S2 Exact Mass 516.309570 PSA 91.06000 LogP 10.27 Index of Refraction 1.574 InChIKey FYPMFJGVHOHGLL-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Primidolol | 67227-55-8 | 2A-9012120 |
| Primidone | 125-33-7 | 2A-9012121 |
| Prisotinol | 78997-40-7 | 2A-9012124 |
| Prizidilol | 59010-44-5 | 2A-9012125 |
| Proadifen hydrochloride | 62-68-0 | 2A-9012126 |
| Procainamide | 51-06-9 | 2A-9012129 |
| Procainamide hydrochloride | 614-39-1 | 2A-9012130 |
| Procarbazine | 671-16-9 | 2A-9012132 |
| Procarbazine hydrochloride | 366-70-1 | 2A-9012133 |
| Procaterol | 72332-33-3 | 2A-9012134 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS