CAS Number550-99-2
SynonymsNaphcon; 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole,hydrochloride; Naphazoline hydrochloride; EINECS 208-989-2; 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazole hydrochloride; 2-(1-Naphthylmethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, hydrochloride (1:1); MFCD00012554; 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride; Naphazoline (hydrochloride)
Molecular FormulaC14H15ClN2
Molecular Weight246.74
Purity98%
Density1.15 g/cm3
Boiling Point440.5ºC at 760 mmHg
Melting Point254-260 °C
AppearanceWhite crystalline powder
EINECS208-989-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 550-99-2 |
| Catalog No. | 2A-9011574 |
| Chinese Name | 盐酸萘甲唑啉 |
| Synonyms | Naphcon; 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole,hydrochloride; Naphazoline hydrochloride; EINECS 208-989-2; 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazole hydrochloride; 2-(1-Naphthylmethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, hydrochloride (1:1); MFCD00012554; 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride; Naphazoline (hydrochloride) |
| Molecular Formula | C14H15ClN2 |
| Molecular Weight | 246.74 |
| Purity | 98 |
| Density | 1.15 g/cm3 |
| Boiling Point | 440.5ºC at 760 mmHg |
| Melting Point | 254-260 °C |
| Appearance | White crystalline powder |
| Water Solubility | 170 g/L (20 ºC) |
| Storage Condition | Ventilated, cool and dry, away from fire sources a |
| Packaging | III |
| Application | Naphazoline hydrochloride is an ocular vasoconstrictor and an imidazoline derivative. |
| EINECS | 208-989-2 |
| HTC | 2934999090 |
| PubChem ID | 329823630 |
| MDL Number | MFCD00012554 |
| SMILES | Cl.C1CN=C(Cc2cccc3ccccc23)N1 |
| InChI | 1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H |
| InChI Key | DJDFFEBSKJCGHC-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 6.1 |
| MSDS | msds/11574_1_550_99_2.pdf |
| Bioactivity | Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.Target: Adrenergic Receptorphazoline hydrochloride is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops. From Wikipedia. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Naphazoline Chemical & Physical Properties Density 1.15 g/cm3 Boiling Point 440.5ºC at 760 mmHg Melting Point 254-260 °C Molecular Formula C14H15ClN2 Molecular Weight 246.735 Flash Point 220.2ºC Exact Mass 246.092377 PSA 24.39000 LogP 2.95040 InChIKey DJDFFEBSKJCGHC-UHFFFAOYSA-N SMILES Cl.c1ccc2c(CC3=NCCN3)cccc2c1 Water Solubility 170 g/L (20 ºC) |
| Use of | Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.Target: Adrenergic Receptorphazoline hydrochloride is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops. From Wikipedia. Properties Articles27 Name Naphazoline hydrochloride Synonym More Synonyms Naphazoline hydrochloride Biological Activity Description Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.Target: Adrenergic Receptorphazoline hydrochloride is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops. From Wikipedia. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Naphazoline Chemical & Physical Properties Exact Mass 246.092377 PSA 24.39000 LogP 2.95040 InChIKey DJDFFEBSKJCGHC-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: Item 1 Poisons. UN number: 2811 Proper Shipping Name: Toxic Solid, Organic, Not Otherwise Specified Packing grade: II |
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