CAS Number97867-33-9
SynonymsFlunase [inj.]; Cipobacter; Ciproflox [inj.]; Ciprobid Eye Drops; Ciproxin [inj.]; Flociprin [inj.]; Ciproxina [inj.]; Quintor Eye Drops; Ificipro; MFCD01759747
Molecular FormulaC20H24O6N3F1
Molecular Weight421.43
Purity98%
Density1.4±0.1 g/cm3
Boiling Point656.4±55.0 °C at 760 mmHg
Melting Point255-257ºC
AppearanceWhite or yellow crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 97867-33-9 |
| Catalog No. | 2A-9009820 |
| Chinese Name | 乳酸环丙沙星 |
| Synonyms | Flunase [inj.]; Cipobacter; Ciproflox [inj.]; Ciprobid Eye Drops; Ciproxin [inj.]; Flociprin [inj.]; Ciproxina [inj.]; Quintor Eye Drops; Ificipro; MFCD01759747 |
| Molecular Formula | C20H24O6N3F1 |
| Molecular Weight | 421.43 |
| Purity | 98 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 656.4±55.0 °C at 760 mmHg |
| Melting Point | 255-257ºC |
| Appearance | White or yellow crystalline powder |
| Storage Condition | Room Temperature |
| Application | Ciprofloxacin lactate (Bay-09867) is an orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage, leading to mitochondrial dysfunction and the p |
| HTC | 2933491000 |
| MDL Number | MFCD01759747 |
| SMILES | CC(O)C(=O)O.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O |
| InChI | InChI=1S/C17H18FN3O3.C3H6O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;1-2(4)3(5)6/h7-10,19H,1-6H2,(H,23,24);2,4H,1H3,(H,5,6) |
| InChI Key | NRBJWZSFNGZBFQ-UHFFFAOYSA-N |
| MSDS | msds/9820_1_97867_33_9.pdf |
| Use of | Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4]. Properties Name 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid,2-hydroxypropanoic acid Synonym More Synonyms Ciprofloxacin Lactate Soluble Biological Activity Description Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [2]. Steenbergen J, et, al. In Vitro and In Vivo Activity of Omadacycline against Two Biothreat Pathogens, Bacillus anthracis and Yersinia pestis. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02434-16. [3]. Hamblin KA, et, al. Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague. Front Microbiol. 2017 Feb 6;8:91. [4]. LeMaire SA, et, al. Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice. JAMA Surg. 2018 Sep 1;153(9):e181804. Chemical & Physical Properties Molecular Formula C20H24FN3O6 Exact Mass 403.154358 PSA 100.87000 Index of Refraction 1.624 InChIKey NRBJWZSFNGZBFQ-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2933491000 |
| Tax Rebate | 9.0% |
| Supervision | None. Minimum tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933491000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:6.5%. General tariff:20.0% |
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