CAS Number87239-81-4
SynonymsR-3763; Cefodox; JP,USP; Cefpodoxime proxetil; Orelox; CS-807; Cefpodoxime 1-(Isopropoxycarbonyloxy)ethyl ester; Podomexef; BANAN; UNII:2TB00A1Z7N; MFCD00864906; cefpodoxime 1-(isopropyloxycarbonyloxy)ethyl ester; cefprodoxime proxetil; Otreon; cefpodoxime-proxetil; Vantin
Molecular FormulaC21H27O9N5S2
Molecular Weight557.61
Purity98%
Density1.6±0.1 g/cm3
Melting Point111-113°C
AppearanceA white or almost white crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 87239-81-4 |
| Catalog No. | 2A-9009665 |
| Chinese Name | 头孢泊肟酯 |
| Synonyms | R-3763; Cefodox; JP,USP; Cefpodoxime proxetil; Orelox; CS-807; Cefpodoxime 1-(Isopropoxycarbonyloxy)ethyl ester; Podomexef; BANAN; UNII:2TB00A1Z7N; MFCD00864906; cefpodoxime 1-(isopropyloxycarbonyloxy)ethyl ester; cefprodoxime proxetil; Otreon; cefpodoxime-proxetil; Vantin |
| Molecular Formula | C21H27O9N5S2 |
| Molecular Weight | 557.61 |
| Purity | 98 |
| Density | 1.6±0.1 g/cm3 |
| Melting Point | 111-113°C |
| Appearance | A white or almost white crystalline powder |
| Storage Condition | -20?C Freezer |
| Application | Cefpodoxime Proxetil is the first oral broad-spectrum antibiotic and is a third-generation cephalosporin. Cefpodoxime Proxetil binds to penicillin binding proteins, inhibits peptidoglycan synthesis, a |
| HTC | 2941905990 |
| MDL Number | MFCD00865088 |
| SMILES | COCC1=C(C(=O)OC(C)OC(=O)OC(C)C)N2C(=O)C(NC(=O)C(=NOC)c3csc(N)n3)C2SC1 |
| InChI | InChI=1S/C21H27N5O9S2/c1-9(2)33-21(30)35-10(3)34-19(29)15-11(6-31-4)7-36-18-14(17(28)26(15)18)24-16(27)13(25-32-5)12-8-37-20(22)23-12/h8-10,14,18H,6-7H2,1-5H3,(H2,22,23)(H,24,27)/b25-13-/t10?,14-,18-/m1/s1 |
| InChI Key | LTINZAODLRIQIX-OBEQYXGQSA-N |
| MSDS | msds/9665_1_87239_81_4.pdf |
| Use of | Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis[1]. Properties Articles40 Name cefpodoxime proxetil Synonym More Synonyms Cefpodoxime Proxetil Biological Activity Description Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Iqbal S, et al. In vitro Spectroscopic studies on drug interaction of cefpodoxime proxetil and H2 receptor blockers. Pak J Pharm Sci. 2019 Mar;32(2 (Supplementary)):881-887. Chemical & Physical Properties Molecular Formula C21H27N5O9S2 Exact Mass 557.125000 PSA 234.51000 Index of Refraction 1.671 InChIKey LTINZAODLRIQIX-OBEQYXGQSA-N Storage condition -20?C Freezer Safety Information Hazard Codes Xi Safety Phrases S26-S36 RIDADR NONH for all modes of transport WGK Germany 3 HS Code 2941905990 Synthetic Route 1-Iodoethyl iso... CAS#:84089-73-6 cefpodoxime CAS#:80210-62-4 Cefpodoxime Proxetil CAS#:87239-81-4 1-((isopropoxyc... CAS#:620962-96-1 Cefpodoxime Proxetil CAS#:87239-81-4 Literature: Rodriguez, Juan C.; Hernandez, Ricardo; Gonzalez, Maritza; Rodriguez, Zalua; Tolon, Blanca; Velez, Herman; Valdes, Barbara; Lopez, Miguel A.; Fini, Adamo Farmaco, 2003 , vol. 58, # 5 p. 363 - 369 7-Aminocephalos... CAS#:957-68-6 Cefpodoxime Proxetil CAS#:87239-81-4 Literature: Farmaco, , vol. 58, # 5 p. 363 - 369 Precursor & DownStream Precursor 9 CAS#:84089-73-6 1-Iodoethyl iso... CAS#:80210-62-4 cefpodoxime CAS#:620962-96-1 1-((isopropoxyc... CAS#:957-68-6 7-Aminocephalos... DownStream 0 |
| Transport Info | Product Name: Cefpodoxime Proxetil |
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