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Cefpodoxime structure, CAS 80210-62-4

Cefpodoxime

CAS Number80210-62-4

SynonymsCefpodoxime Acid; cefpodoxime; cefpodoxima; U 76253A

Molecular FormulaC15H17N5O6S2

Molecular Weight427.46

Purity98%

Density1.8±0.1 g/cm3

Boiling Point

Melting Point200-202ºC

Flash Point

AppearanceWhite to light yellow powder

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Cat. No.: 2A-9009664 Purity: 98%
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Quality Control of [ 80210-62-4 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number80210-62-4
Catalog No.2A-9009664
Chinese Name头孢泊肟
SynonymsCefpodoxime Acid; cefpodoxime; cefpodoxima; U 76253A
Molecular FormulaC15H17N5O6S2
Molecular Weight427.46
Purity98
Density1.8±0.1 g/cm3
Melting Point200-202ºC
AppearanceWhite to light yellow powder
Storage Condition-20°C, sealed, dry
ApplicationCefpodoxime (cefpodoxime acid) is an antibiotic effective against both Gram-positive and Gram-negative bacteria. Cefpodoxime inhibits most cells in the microbiota. Cefpodoxime can be used in the study
PubChem ID329754145
MDL NumberMFCD00864906
SMILESO=C(/C(C1=CSC(N)=N1)=N\OC)N[C@H](C2=O)[C@]3([H])N2C(C(O)=O)=C(COC)CS3
InChI1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
InChI KeyWYUSVOMTXWRGEK-HBWVYFAYSA-N
Beilstein/REAXYS6021381
NACRES CodeNA.24
UNSPSC41116107
Hazard SymbolsTransport
MSDSmsds/9664_1_80210_62_4.pdf
BioactivityCefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial In Vitro Cefpodoxime (Cefpodoxime acid) inhibits gram-negative anaerobic rods (Bacteroidaceae) with MIC values of 0.125-4 mg/L. Cefpodoxime inhibits Veillonella parvula with MIC values of 0.25-8 mg/L. Cefpodoxime inhibits Peptostreptococcus micros, Peptostreptococcus asaccharolyticus and Ruminococcus bromii with MIC values of <2 mg/L[1]. Cefpodoxime (Cefpodoxime acid) inhibits bacterial populations of S. pneumoniae and S. pyogenes. cfu[2]. In Vivo Cephalosporins (2.5-50 mg/kg; p.o.; every 8 hours; for 48 hours) have good curative effect in mice[3]. Animal Model: Female Swiss CD1 mice[3] Dosage: 2.5, 5, 10, 25, 40 and 50 mg/kg Administration: Oral administration; every 8 hours; for 48 hours Result: Efficacy was obtained with values of >350. References [1]. Werner H, et, al. Comparative in vitro activity of cefpodoxime against anaerobes other than Bacteroides fragilis. Infection. 1991 Sep-Oct;19(5):377-9. [2]. Valentini S, et, al. In-vitro evaluation of cefpodoxime. J Antimicrob Chemother. 1994 Mar;33(3):495-508. [3]. Pérez-Trallero E, et, al. Prediction of in-vivo efficacy by in-vitro early bactericidal activity with oral beta-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin. J Chemother. 2001 Apr;13(2):118-25. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Melting Point 200-202ºC Molecular Formula C15H17N5O6S2 Molecular Weight 427.455 Exact Mass 427.062012 PSA 209.98000 LogP 0.94 Index of Refraction 1.780 InChIKey WYUSVOMTXWRGEK-NOZJJQNGSA-N SMILES COCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOC)c3csc(N)n3)C2SC1
Use ofCefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research[1][2]. Properties Articles15 Name cefpodoxime Synonym More Synonyms cefpodoxime Biological Activity Description Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Werner H, et, al. Comparative in vitro activity of cefpodoxime against anaerobes other than Bacteroides fragilis. Infection. 1991 Sep-Oct;19(5):377-9. [2]. Valentini S, et, al. In-vitro evaluation of cefpodoxime. J Antimicrob Chemother. 1994 Mar;33(3):495-508. [3]. Pérez-Trallero E, et, al. Prediction of in-vivo efficacy by in-vitro early bactericidal activity with oral beta-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin. J Chemother. 2001 Apr;13(2):118-25. Chemical & Physical Properties Molecular Formula C15H17N5O6S2 Exact Mass 427.062012 PSA 209.98000 Index of Refraction 1.780 InChIKey WYUSVOMTXWRGEK-NOZJJQNGSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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