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Carbazochrome sodium sulfonate structure, CAS 51460-26-5

Carbazochrome sodium sulfonate

CAS Number51460-26-5

SynonymsCarbazochrome sodium sulfonate; EINECS 257-217-0; ADRENOCHROME SEMICARBAZONE SULFONATE SODIUM SALT; Sodium (Z)-5-(2-carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate; Sodium 5-(carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate; MFCD00211294; Carbazochrome sodium sulfonate (AC-17)

Molecular FormulaC10H11N4NaO5S

Molecular Weight322.277

Purity98%

Density

Boiling Point

Melting Point

Flash Point

AppearanceOrange yellow crystalline powder

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9009574 Purity: 98%
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Quality Control of [ 51460-26-5 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number51460-26-5
Catalog No.2A-9009574
Chinese Name卡络磺钠
SynonymsCarbazochrome sodium sulfonate; EINECS 257-217-0; ADRENOCHROME SEMICARBAZONE SULFONATE SODIUM SALT; Sodium (Z)-5-(2-carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate; Sodium 5-(carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate; MFCD00211294; Carbazochrome sodium sulfonate (AC-17)
Molecular FormulaC10H11N4NaO5S
Molecular Weight322.277
Purity98
AppearanceOrange yellow crystalline powder
Storage ConditionKeep the receptacle sealed, stored in a cool, dry
ApplicationCarbazochrome (AC-17) sodium sulfonate is an anti-bleeding agent.
HTC2933990090
MDL NumberMFCD00867493
SMILESCN1c2cc(O)c(N=NC(N)=O)cc2CC1S(=O)(=O)[O-].[Na+]
InChIInChI=1S/C10H12N4O5S.Na/c1-14-7-4-8(15)6(12-13-10(11)16)2-5(7)3-9(14)20(17,18)19;/h2,4,9H,3H2,1H3,(H3,11,13,16)(H,17,18,19);/q;+1/p-1/b12-6-;
InChI KeyPDZKPUQLQNDXMQ-UHFFFAOYSA-M
Hazard SymbolsTransport
MSDSmsds/9574_1_51460_26_5.pdf
BioactivityCarbazochrome(AC-17) is an antihemorrhagic agent.Target: OthersCarbazochrome is an antihemorrhagic agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids. Carbazochrome interacts with α-adrenoreceptors on surface of platelets, which are coupled to Gq protein and initiate PLC IP3/DAG pathway to increase intracellular free calcium concentration with these subsequent actions. Activates PLA2 and induce arachidonic acid pathway to synthese endoperoxides (TxA2, thromboxane A2). Calcium binds to calmodulin which then binds and activates myosin light-chain kinase, that will enable the myosin crossbridge to bind to the actin filament and allow contraction to begin. This will change platelet's shape and induce release of serotonin, ADP, vWF (Von Willebrand factor), PAF (Platelet-activating factor) to promote further aggregation and adhesion. From Wikipedia. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Carbazochrome Chemical & Physical Properties Molecular Formula C10H11N4NaO5S Molecular Weight 322.27 PSA 181.06000 LogP 0.52750 InChIKey PDZKPUQLQNDXMQ-UHFFFAOYSA-M SMILES CN1c2cc(O)c(N=NC(N)=O)cc2CC1S(=O)(=O)[O-].[Na+]
Use ofProperties Name Carbazochrome Sodium Sulfonate Synonym More Synonyms Carbazochrome sodium sulfonate (AC-17) Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Carbazochrome Chemical & Physical Properties Molecular Formula C10H11N4NaO5S PSA 181.06000 LogP 0.52750 InChIKey PDZKPUQLQNDXMQ-UHFFFAOYSA-M
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip.
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