CAS Number70724-25-3
SynonymsCarbamic acid, ethyl-, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester; Carbamic acid, N-ethyl-, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester; 1-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate; [1-(6,7-dimethoxyphthalazin-1-yl)piperidin-4-yl] N-ethylcarbamate; 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl ethylcarbamate; carbazeran; Ethylcarbamic Acid 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl Ester
Molecular FormulaC18H24N4O4
Molecular Weight360.41
Purity≥95 (HPLC)%
Density1.3±0.1 g/cm3
Boiling Point595.6±50.0 °C at 760 mmHg
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 70724-25-3 |
| Catalog No. | 2A-9009573 |
| Chinese Name | 卡巴泽伦 |
| Synonyms | Carbamic acid, ethyl-, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester; Carbamic acid, N-ethyl-, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester; 1-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate; [1-(6,7-dimethoxyphthalazin-1-yl)piperidin-4-yl] N-ethylcarbamate; 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl ethylcarbamate; carbazeran; Ethylcarbamic Acid 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl Ester |
| Molecular Formula | C18H24N4O4 |
| Molecular Weight | 360.41 |
| Purity | ≥95 (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 595.6±50.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8°C |
| Application | Carbazelan is a potent phosphodiesterase inhibitor and a substrate of aldehyde oxidase. Carbazelan can be used in the study of metabolic diseases [1]. |
| HTC | 2933990090 |
| PubChem ID | 329825313 |
| MDL Number | MFCD00867107 |
| SMILES | CCNC(=O)OC1CCN(CC1)c2nncc3cc(OC)c(OC)cc23 |
| InChI | 1S/C18H24N4O4/c1-4-19-18(23)26-13-5-7-22(8-6-13)17-14-10-16(25-3)15(24-2)9-12(14)11-20-21-17/h9-11,13H,4-8H2,1-3H3,(H,19,23) |
| InChI Key | QJGVXJYGDBSPSJ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 41106305 |
| Hazard Symbols | Transport |
| MSDS | msds/9573_1_70724_25_3.pdf |
| Bioactivity | Carbazeran, a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran can be used for the research of metabolic disease[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Metabolic Disease References [1]. Uehara S, et al. Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metab Dispos. 2020 Jul;48(7):580-586. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 595.6±50.0 °C at 760 mmHg Molecular Formula C18H24N4O4 Molecular Weight 360.408 Flash Point 314.0±30.1 °C Exact Mass 360.179749 PSA 85.81000 LogP 1.38 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.600 InChIKey QJGVXJYGDBSPSJ-UHFFFAOYSA-N SMILES CCNC(=O)OC1CCN(c2nncc3cc(OC)c(OC)cc23)CC1 Storage condition 2-8°C |
| Use of | Carbazeran, a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran can be used for the research of metabolic disease[1]. Properties Articles12 Name 1-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate Synonym More Synonyms carbazeran Biological Activity Description Carbazeran, a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran can be used for the research of metabolic disease[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Metabolic Disease References [1]. Uehara S, et al. Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metab Dispos. 2020 Jul;48(7):580-586. Chemical & Physical Properties Molecular Formula C18H24N4O4 Exact Mass 360.179749 PSA 85.81000 Index of Refraction 1.600 InChIKey QJGVXJYGDBSPSJ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (Carbazeran) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Carbazeran) International air transport hazard regulations: Toxic solid, organic, n.o.s. (Carbazeran) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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