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Hydrocortisone sodium phosphate structure, CAS 6000-74-4

Hydrocortisone sodium phosphate

CAS Number6000-74-4

Synonymscortisol sodium phosphate; Physiocortison; Hydrocortisone Sodium Phosphate; EINECS 227-843-9; Efcortesol; Actocortin; (11b)-11,17-Dihydroxy-21-(phosphonooxy)pregn-4-ene-3,20-dione Disodium Salt; Cleiton; Disodium (11β)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl phosphate; Hydrocortisone 21-phosphate disodium salt; Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, sodium salt, (11β)- (1:2); Idracemi; Cortisol 21-(Dihydrogen Phosphate) Disodium Salt; Hidroaltesona; MFCD00152562; Actocortina

Molecular FormulaC21H29Na2O8P

Molecular Weight486.404

Purity98%

Density

Boiling Point669.9ºC at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

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Cat. No.: 2A-9008010 Purity: 98%
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Quality Control of [ 6000-74-4 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number6000-74-4
Catalog No.2A-9008010
Chinese Name氢化可的松磷酸钠
Synonymscortisol sodium phosphate; Physiocortison; Hydrocortisone Sodium Phosphate; EINECS 227-843-9; Efcortesol; Actocortin; (11b)-11,17-Dihydroxy-21-(phosphonooxy)pregn-4-ene-3,20-dione Disodium Salt; Cleiton; Disodium (11β)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl phosphate; Hydrocortisone 21-phosphate disodium salt; Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, sodium salt, (11β)- (1:2); Idracemi; Cortisol 21-(Dihydrogen Phosphate) Disodium Salt; Hidroaltesona; MFCD00152562; Actocortina
Molecular FormulaC21H29Na2O8P
Molecular Weight486.404
Purity98
Boiling Point669.9ºC at 760 mmHg
Storage ConditionRoom Temperature
ApplicationHydrocortisone phosphate (sodium) (hydrocortisol 21 phosphate (sodium)) is a soft steroid with low anti-inflammatory properties and a short duration of action. Cortisone phosphate (sodium) (cortisone
SMILESCC12CCC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)COP(=O)(O)O.[Na+].[Na+]
InChIInChI=1S/C21H31O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h9,14-16,18,23,25H,3-8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14?,15?,16?,18?,19?,20?,21-;;/m0../s1
InChI KeyRYJIRNNXCHOUTQ-OJJGEMKLSA-N
Hazard SymbolsTransport
BioactivityHydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) can be used for the research for several ocular conditions and gastric ulcers[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Others >> Others In Vivo Hydrocortisone phosphate (sodium) (2.5 mg/kg, ip., daily) delays healing of established gastric ulcers induced by acetic acid in the rat[2]. Animal Model: Wistar rats[2] Dosage: 2.5 mg/kg Administration: 2.5 mg/kg, ip., daily Result: Resulted in a significant delay of ulcer healing induced by acetic acid. References [1]. Carlo Cagini, et al. Kinetics of hydrocortisone sodium phosphate penetration into the human aqueous humor after topical application. Int J Clin Pract. 2021 Dec;75(12):e14987. [2]. H Kuwayama, et al. Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. Am J Med. 1991 Aug 8;91(2A):15S-19S. Chemical & Physical Properties Boiling Point 669.9ºC at 760 mmHg Molecular Formula C21H29Na2O8P Molecular Weight 486.404 Exact Mass 486.139557 PSA 156.83000 LogP 2.77500 InChIKey RYJIRNNXCHOUTQ-OJJGEMKLSA-N SMILES CC12CCC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)COP(=O)(O)O.[Na+].[Na+]
Use ofHydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) can be used for the research for several ocular conditions and gastric ulcers[1]. Properties Name cortisol sodium phosphate Synonym More Synonyms Cleiton Biological Activity Description Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) can be used for the research for several ocular conditions and gastric ulcers[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Carlo Cagini, et al. Kinetics of hydrocortisone sodium phosphate penetration into the human aqueous humor after topical application. Int J Clin Pract. 2021 Dec;75(12):e14987. [2]. H Kuwayama, et al. Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. Am J Med. 1991 Aug 8;91(2A):15S-19S. Chemical & Physical Properties Molecular Formula C21H29Na2O8P Exact Mass 486.139557 PSA 156.83000 LogP 2.77500 InChIKey RYJIRNNXCHOUTQ-OJJGEMKLSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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