CAS Number71-58-9
SynonymsG-Farlutal; Progesterone, 17-hydroxy-6α-methyl-, acetate; 17a-Hydroxy-6a-methylpregn-4-ene-3,20-dione acetate; 17a-Hydroxy-6a-methylprogesterone acetate; 17-Acetoxy-6α-methylprogesterone; MFCD00010483; Medroxyprogesterone 17-acetate; 17α-Acetoxy-6-α-methylpregn-4-ene-3,20-dione; Provest; Sodelut G; EINECS 200-757-9; (6α)-6-Methyl-3,20-dioxopregn-4-en-17-yl acetate; 6α-Methyl-17α-hydroxyprogesterone acetate; 6a-Methyl-4-pregnene-3,20-dion-17a-ol acetate; Medroxiprogesteron Acetate; 17α-Acetoxy-6α-methylprogesterone; (6a)-6-methyl-3,20-dioxopregn-4-en-17-yl acetate; 17α-acetoxy-6α-methyl-pregn-4-ene-3,20-dione; 6α-Methyl-17α-acetoxypregn-4-ene-3,20-dione; 17α-Hydroxy-6α-methylpregn-4-ene-3,20-dione acetate; Gestoral; 17a-Acetoxy-6a-methylpregn-4-ene-3,20-dione; Medroxyprogesterone acetate; G
Molecular FormulaC24H34O4
Molecular Weight386.52
Purity97%
Density1.1±0.1 g/cm3
Boiling Point496.4±45.0 °C at 760 mmHg
Melting Point206-207 °C (lit.)
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 71-58-9 |
| Catalog No. | 2A-9008181 |
| Chinese Name | 安宫黄体酮 |
| Synonyms | G-Farlutal; Progesterone, 17-hydroxy-6α-methyl-, acetate; 17a-Hydroxy-6a-methylpregn-4-ene-3,20-dione acetate; 17a-Hydroxy-6a-methylprogesterone acetate; 17-Acetoxy-6α-methylprogesterone; MFCD00010483; Medroxyprogesterone 17-acetate; 17α-Acetoxy-6-α-methylpregn-4-ene-3,20-dione; Provest; Sodelut G; EINECS 200-757-9; (6α)-6-Methyl-3,20-dioxopregn-4-en-17-yl acetate; 6α-Methyl-17α-hydroxyprogesterone acetate; 6a-Methyl-4-pregnene-3,20-dion-17a-ol acetate; Medroxiprogesteron Acetate; 17α-Acetoxy-6α-methylprogesterone; (6a)-6-methyl-3,20-dioxopregn-4-en-17-yl acetate; 17α-acetoxy-6α-methyl-pregn-4-ene-3,20-dione; 6α-Methyl-17α-acetoxypregn-4-ene-3,20-dione; 17α-Hydroxy-6α-methylpregn-4-ene-3,20-dione acetate; Gestoral; 17a-Acetoxy-6a-methylpregn-4-ene-3,20-dione; Medroxyprogesterone acetate; G |
| Molecular Formula | C24H34O4 |
| Molecular Weight | 386.52 |
| Purity | 97 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 496.4±45.0 °C at 760 mmHg |
| Melting Point | 206-207 °C (lit.) |
| Appearance | white powder |
| Water Solubility | <0.1 g/100 mL at 23 ºC |
| Storage Condition | This product should be sealed, cool, dry and prote |
| Application | Medroxyprogesterone acetate is a progesterone receptor agonist and is a synthetic variant of the human hormone progesterone. |
| PubChem ID | 329750335 |
| MDL Number | MFCD00010483 |
| SMILES | [H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O |
| InChI | 1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1 |
| InChI Key | PSGAAPLEWMOORI-PEINSRQWSA-N |
| Beilstein/REAXYS | 2066112 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/8181_1_71_58_9.pdf |
| Bioactivity | Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.Target: Progesterone ReceptorMedroxyprogesterone acetate(MPA) is a steroidal progestin, a synthetic variant of the human hormone progesterone. It is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications. MPA is a more potent derivative of its parent compound medroxyprogesterone (MP). While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate, what is normally being administered is MPA and not MP [1, 2]. Related Catalog Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology References [1]. Schindler, A.E., et al., Classification and pharmacology of progestins. Maturitas, 2008. 61(1-2): p. 171-80. [2]. Lenco, W., M. McKnight, and A.S. Macdonald, Effects of cortisone acetate, methylprednisolone and medroxyprogesterone on wound contracture and epithelization in rabbits. Ann Surg, 1975. 181(1): p. 67-73. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 496.4±45.0 °C at 760 mmHg Melting Point 206-207 °C(lit.) Molecular Formula C24H34O4 Molecular Weight 386.524 Flash Point 213.2±28.8 °C Exact Mass 386.245697 PSA 60.44000 LogP 4.11 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.539 InChIKey PSGAAPLEWMOORI-GDXVCIIOSA-N SMILES CC(=O)OC1(C(C)=O)CCC2C3CC(C)C4=CC(=O)CCC4(C)C3CCC21C Storage condition Refrigerator Stability Stable, but weakly air and light sensitive. Incompatible with strong oxidizing agents. Water Solubility <0.1 g/100 mL at 23 ºC |
| Use of | Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.Target: Progesterone ReceptorMedroxyprogesterone acetate(MPA) is a steroidal progestin, a synthetic variant of the human hormone progesterone. It is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications. MPA is a more potent derivative of its parent compound medroxyprogesterone (MP). While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate, what is normally being administered is MPA and not MP [1, 2]. Properties Articles117 Name medroxyprogesterone acetate Synonym More Synonyms Medroxyprogesterone 17-acetate Biological Activity Description Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.Target: Progesterone ReceptorMedroxyprogesterone acetate(MPA) is a steroidal progestin, a synthetic variant of the human hormone progesterone. It is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications. MPA is a more potent derivative of its parent compound medroxyprogesterone (MP). While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate, what is normally being administered is MPA and not MP [1, 2]. Related Catalog Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology References [1]. Schindler, A.E., et al., Classification and pharmacology of progestins. Maturitas, 2008. 61(1-2): p. 171-80. [2]. Lenco, W., M. McKnight, and A.S. Macdonald, Effects of cortisone acetate, methylprednisolone and medroxyprogesterone on wound contracture and epithelization in rabbits. Ann Surg, 1975. 181(1): p. 67-73. Chemical & Physical Properties Molecular Formula C24H34O4 Exact Mass 386.245697 PSA 60.44000 Index of Refraction 1.539 InChIKey PSGAAPLEWMOORI-GDXVCIIOSA-N Storage condition Refrigerator Stability Stable, but weakly air and light sensitive. Incompatible with strong oxidizing agents. |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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