CAS Number4046-02-0
Synonymsethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; MFCD00009190; 4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester; Ferulic acid ethyl ester; Ethyl 4-Hydroxy-3-MethoxycinnaMate; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester; EINECS 223-745-5; Ethyl Ferulate; Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
Molecular FormulaHOC6H3(OCH3)CH=CHCO2C2H5
Molecular Weight222.24
Purity98%
Density1.2±0.1 g/cm3
Boiling Point164-166 °C/0.5 mmHg (lit.)
Melting Point63-65 °C (lit.)
Appearancesolid
EINECS223-745-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 4046-02-0 |
| Catalog No. | 2A-9007807 |
| Chinese Name | 阿魏酸乙酯 |
| Synonyms | ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; MFCD00009190; 4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester; Ferulic acid ethyl ester; Ethyl 4-Hydroxy-3-MethoxycinnaMate; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester; EINECS 223-745-5; Ethyl Ferulate; Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate |
| Molecular Formula | HOC6H3(OCH3)CH=CHCO2C2H5 |
| Molecular Weight | 222.24 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 164-166 °C/0.5 mmHg (lit.) |
| Melting Point | 63-65 °C (lit.) |
| Appearance | solid |
| Water Solubility | Soluble in: methanol |
| Storage Condition | Store at room temperature, away from light, in a v |
| Application | Ethyl ferulate, a natural lipophilic derivative of ferulic acid isolated from anise, induces heme oxygenase 1 (HO-1) and protects rat neurons from oxidative stress. Ethyl ferulate also protects neuron |
| EINECS | 223-745-5 |
| HTC | 2918990090 |
| PubChem ID | 24859274 |
| MDL Number | MFCD00009190 |
| SMILES | CCOC(=O)\C=C\c1ccc(O)c(OC)c1 |
| InChI | 1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+ |
| InChI Key | ATJVZXXHKSYELS-FNORWQNLSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/7807_1_4046_02_0.pdf |
| Bioactivity | Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8. [2]. Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 382.3±0.0 °C at 760 mmHg Melting Point 63-65 °C(lit.) Molecular Formula C12H14O4 Molecular Weight 222.24 Flash Point 132.5±17.2 °C Exact Mass 222.089203 PSA 55.76000 LogP 1.94 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.566 InChIKey ATJVZXXHKSYELS-FNORWQNLSA-N SMILES CCOC(=O)C=Cc1ccc(O)c(OC)c1 |
| Use of | Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2]. Properties Articles26 Name Ethyl 4'-hydroxy-3'-methoxycinnamate Synonym More Synonyms Ethyl ferulate Biological Activity Description Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8. [2]. Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58. Chemical & Physical Properties Molecular Formula C12H14O4 Exact Mass 222.089203 PSA 55.76000 Index of Refraction 1.566 InChIKey ATJVZXXHKSYELS-FNORWQNLSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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