CAS Number149647-78-9
SynonymsSAHA; Suberoylanilidehydroxamic Acid; N-Hydroxy-N'-phenyloctanediamide; M344; Vorinostat/SAHA; Vorinostat; suberoylanilide hydroxamic acid; suberanilohydroxamic acid; Zolinza
Molecular FormulaC14H20N2O3
Molecular Weight264.32
Purity≥98 (HPLC)%
Density1.2±0.1 g/cm3
Melting Point161-162°C
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 149647-78-9 |
| Catalog No. | 2A-9072360 |
| Chinese Name | 伏立诺他 |
| Synonyms | SAHA; Suberoylanilidehydroxamic Acid; N-Hydroxy-N'-phenyloctanediamide; M344; Vorinostat/SAHA; Vorinostat; suberoylanilide hydroxamic acid; suberanilohydroxamic acid; Zolinza |
| Molecular Formula | C14H20N2O3 |
| Molecular Weight | 264.32 |
| Purity | ≥98 (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Melting Point | 161-162°C |
| Appearance | powder |
| Water Solubility | Water solubility: virtually insoluble; water solub |
| Storage Condition | -20°C Freezer |
| Application | Vorinostat is a potent, orally available inhibitor of HDAC1, HDAC2, HDAC3 (Class I), HDAC7 (Class II) and Class IV (HDAC11) with ID50 values of 10 nM and 20 nM for HDAC1/3, respectively. |
| HTC | 29349990 |
| PubChem ID | 329825127 |
| MDL Number | MFCD00945317 |
| SMILES | ONC(=O)CCCCCCC(=O)Nc1ccccc1 |
| InChI | 1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) |
| InChI Key | WAEXFXRVDQXREF-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/72360_1_149647_78_9.pdf |
| Bioactivity | Chemical & Physical Properties |
| Use of | Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV ), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Properties Articles236 Biological Activity Chemical & Physical Properties |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards N-Hydroxy-N'-phenyl suberamide Modification number: 4 Module 14. Shipping information UN number: not specified |
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