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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > 2,4-Heptadienamide,7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-
2,4-Heptadienamide,7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo- structure, CAS 58880-19-6

2,4-Heptadienamide,7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-

CAS Number58880-19-6

SynonymsAntibiotic A-300; (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; (R)-Trichostatin A; TSA; Trichostatin A; 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide; (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide

Molecular FormulaC17H22N2O3

Molecular Weight302.37

Purity

Density1.1±0.1 g/cm3

Boiling Point

Melting Point141-143ºC

Flash Point

Appearanceoff-white powder

EINECS

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Symbol

Signal Word

Cat. No.: 2A-9072359 Purity:
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Quality Control of [ 58880-19-6 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number58880-19-6
Catalog No.2A-9072359
Chinese Name曲古柳菌素A
SynonymsAntibiotic A-300; (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; (R)-Trichostatin A; TSA; Trichostatin A; 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide; (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
Molecular FormulaC17H22N2O3
Molecular Weight302.37
Density1.1±0.1 g/cm3
Melting Point141-143ºC
Appearanceoff-white powder
Water SolubilitySlightly soluble: alcohol; very slightly soluble:
Storage Condition-20℃
ApplicationTrichostatin A is a potent and specific histone deacetylase class I and II (HDAC class I/II) inhibitor with an IC50 value of 1.8 nM for HDAC.
HTC2924299090
PubChem ID329830233
SMILESCC(C=CC(=O)NO)=CC(C)C(=O)c1ccc(N(C)C)cc1
InChIInChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+
InChI KeyRTKIYFITIVXBLE-WKWSCTOISA-N
BioactivityChemical & Physical Properties
Use ofTrichostatin A is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC. Properties Articles582 Biological Activity Chemical & Physical Properties
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 30.0%
Transport InfoProduct name: Purity: 99.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified
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