![3H-Naphtho[2,1-b]pyran-3-one,1,2-dihydro- structure, CAS 5690-03-9](/structures/80000/72357_1_5690_03_9.png)
CAS Number5690-03-9
SynonymsSplitomicin; 1,2-dihydrobenzo[f]chromen-3-one; 1,2-Dihydro-3H-benzo[f]chromen-3-one; MFCD03792600
Molecular FormulaC13H10O2
Molecular Weight198.22
Density1.3±0.1 g/cm3
Boiling Point383.6±17.0 °C at 760 mmHg
Melting Point73-74.5℃
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5690-03-9 |
| Catalog No. | 2A-9072357 |
| Chinese Name | 斯普利特麻一辛 |
| Synonyms | Splitomicin; 1,2-dihydrobenzo[f]chromen-3-one; 1,2-Dihydro-3H-benzo[f]chromen-3-one; MFCD03792600 |
| Molecular Formula | C13H10O2 |
| Molecular Weight | 198.22 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 383.6±17.0 °C at 760 mmHg |
| Melting Point | 73-74.5℃ |
| Appearance | solid |
| Storage Condition | Avoid light, keep in a cool and dry place, sealed |
| Application | Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits the NAD+-dependent HDAC activity of Sir2 protein. Splitomicin inhibits HDAC in yeast extract with an IC50 of 60 μM. |
| HTC | 2914399090 |
| PubChem ID | 5614465 |
| SMILES | O=C1CCc2c(ccc3ccccc23)O1 |
| InChI | InChI=1S/C13H10O2/c14-13-8-6-11-10-4-2-1-3-9(10)5-7-12(11)15-13/h1-5,7H,6,8H2 |
| InChI Key | ISFPDBUKMJDAJH-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Chemical & Physical Properties |
| Use of | Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD+-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 μM[1]. Properties Biological Activity Chemical & Physical Properties |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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