| Chemical & Physical Properties | |
|---|---|
| CAS Number | 38937-66-5 |
| Catalog No. | 2A-9072355 |
| Chinese Name | 软木肟酸 |
| Synonyms | octane-1,8-dihydroxamic acid; N,N'-Dihydroxyoctanediamide; MFCD00192455 |
| Molecular Formula | [-(CH2)3CONHOH]2 |
| Molecular Weight | 204.22 |
| Purity | 95 |
| Density | 1.2±0.1 g/cm3 |
| Melting Point | 153-155 °C (lit.) |
| Appearance | lyophilized powder |
| Water Solubility | H2O: soluble |
| Storage Condition | −20°C |
| Application | Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive, cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively. Suberoyl bis-hydroxamic a |
| HTC | 2924199090 |
| PubChem ID | 24864150 |
| MDL Number | MFCD00192455 |
| SMILES | ONC(=O)CCCCCCC(=O)NO |
| InChI | 1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12) |
| InChI Key | IDQPVOFTURLJPT-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/72355_1_38937_66_5.pdf |
| Bioactivity | Chemical & Physical Properties |
| Use of | Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively[1].Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways[2].Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC)[3]. Properties Articles10 Biological Activity Chemical & Physical Properties |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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| Browse all Specialty Chemicals products » | ||
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