CAS Number941678-49-5
SynonymsRuxolitinib; ((3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile); (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propionitrile; UNII:82S8X8XX8H; (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; INCB018424
Molecular FormulaC17H18N6
Molecular Weight306.37
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point592.6±50.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 941678-49-5 |
| Catalog No. | 2A-9059284 |
| Chinese Name | 鲁索利替尼 |
| Synonyms | Ruxolitinib; ((3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile); (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propionitrile; UNII:82S8X8XX8H; (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; INCB018424 |
| Molecular Formula | C17H18N6 |
| Molecular Weight | 306.37 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 592.6±50.0 °C at 760 mmHg |
| Storage Condition | 2-8°C |
| Application | Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively. The selectivity is more than 130 times that of JAK3. |
| MDL Number | MFCD12031592 |
| SMILES | N#CCC(C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 |
| InChI Key | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| MSDS | msds/59284_1_941678_49_5.pdf |
| Transport Info | Product Name: Ruxolitinib |
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