CAS Number142273-20-9
Synonyms9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one; 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one; Kenpaullone; MFCD02683595; 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one; NSC-664704
Molecular FormulaC16H11BrN2O
Molecular Weight327.18
Purity≥95 (HPLC)%
Density1.6±0.1 g/cm3
Boiling Point613.0±45.0 °C at 760 mmHg
Melting Point>300ºC (dec.)
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 142273-20-9 |
| Catalog No. | 2A-1198812 |
| Chinese Name | 肯帕罗酮 |
| Synonyms | 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one; 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one; Kenpaullone; MFCD02683595; 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one; NSC-664704 |
| Molecular Formula | C16H11BrN2O |
| Molecular Weight | 327.18 |
| Purity | ≥95 (HPLC) |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 613.0±45.0 °C at 760 mmHg |
| Melting Point | >300ºC (dec.) |
| Appearance | solid |
| Water Solubility | DMSO: 18 mg/mL, clear, yellow |
| Storage Condition | 2-8°C |
| Application | Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β with IC50 values of 0.4 μM and 23 nM respectively. It also inhibits the activities of CDK2/cyclin A, CDK2/cyclin E and CDK5/p25 with IC5 |
| MDL Number | MFCD02683595 |
| SMILES | Brc1cc2c([nH]c3c2CC(=O)Nc4c3cccc4)cc1 |
| InChI | 1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20) |
| InChI Key | QQUXFYAWXPMDOE-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/200754_1_142273_20_9.pdf |
| Transport Info | Product Name: Kamparolone |
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