| Chemical & Physical Properties | |
|---|---|
| CAS Number | 22144-76-9 |
| Catalog No. | 2A-1177711 |
| Chinese Name | 细胞松驰素 C |
| Synonyms | EINECS 244-803-6; Cytochalasin C from Metarrhizium anisopliae; MFCD00066080 |
| Molecular Formula | C30H37NO6 |
| Molecular Weight | 507.618 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 714.3±60.0 °C at 760 mmHg |
| Melting Point | 260-264ºC |
| Water Solubility | methylene chloride: 5 mg/mL, clear, colorless |
| Storage Condition | Sealed in a cool, dry environment |
| Packaging | I |
| Application | Cytochalasin C is a cell-penetrating mycotoxin that induces the formation of nuclear rods. Cytochalasin C is 10 times less toxic than Cytochalasin D in mice. |
| SMILES | CC(=O)OC1C=CC(C)(O)C(=O)C(C)CC=CC2C(O)C(C)=C(C)C3C(Cc4ccccc4)NC(=O)C123 |
| InChI | InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17,22-26,33,36H,10,16H2,1-5H3,(H,31,35)/b13-9-,15-14-/t17-,22-,23?,24+,25-,26+,29+,30+/m0/s1 |
| InChI Key | NAIODHJWOHMDJX-WISUYLHISA-N |
| Hazard Symbols | 6.1(a) |
| Bioactivity | Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Foissner I, et al. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells. Plant Cell Physiol. 2007 Apr;48(4):585-97. [2]. Yahara I, et al. Correlation between effects of 24 different cytochalasins on cellular structures and cellular eventsand those on actin in vitro. J Cell Biol. 1982 Jan;92(1):69-78. [3]. Trendowski M, et al. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerateddoses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumormodel systems in vivo. In Vivo. 2014 Nov-Dec;28(6):1021-31. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 714.3±60.0 °C at 760 mmHg Melting Point 260-264ºC Molecular Formula C30H37NO6 Molecular Weight 507.618 Flash Point 385.8±32.9 °C Exact Mass 507.262085 PSA 112.93000 LogP 2.81 Vapour Pressure 0.0±2.4 mmHg at 25°C Index of Refraction 1.602 InChIKey NAIODHJWOHMDJX-WISUYLHISA-N SMILES CC(=O)OC1C=CC(C)(O)C(=O)C(C)CC=CC2C(O)C(C)=C(C)C3C(Cc4ccccc4)NC(=O)C123 Storage condition −20°C Water Solubility methylene chloride: 5 mg/mL, clear, colorless |
| Use of | Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3]. Properties Articles14 Name cytochalasin c Synonym More Synonyms Cytochalasin C Biological Activity Description Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Foissner I, et al. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells. Plant Cell Physiol. 2007 Apr;48(4):585-97. [3]. Trendowski M, et al. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerateddoses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumormodel systems in vivo. In Vivo. 2014 Nov-Dec;28(6):1021-31. Chemical & Physical Properties Molecular Formula C30H37NO6 Exact Mass 507.262085 PSA 112.93000 Index of Refraction 1.602 InChIKey NAIODHJWOHMDJX-WISUYLHISA-N |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Danger Regulations: 1544 International Maritime Transport Danger Regulations: 1544 International Air Transport Danger Regulations: 1544 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: ALKALOIDS, SOLID, N.O.S. (Cytochalasin C Metarhizium anisopliae) IMDG Code: ALKALOIDS, SOLID, N.O.S. (Cytochalasin C Metarhizium anisopliae) International Air Transport Risk Regulations: Alkaloids, solid, n.o.s. (Cytochalasin C Metarhizium anisopliae) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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