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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > CHAETOGLOBOSIN A
CHAETOGLOBOSIN A structure, CAS 50335-03-0

CHAETOGLOBOSIN A

CAS Number50335-03-0

Synonymschaetoglobosins; Chaetoglobosin A; CHAETOGLOBOSIN A; CHAETOGLOBOSIN; CHAETOGLOBOSINB; 18-dimethyl-,(7s,13e,16s,17e,19r,21e)-ol-3-yl)-1; CHAETOGLOBOSINE; (13)cytochalasa-13,17,21-triene-1,20,23-trione,6,7-epoxy-19-hydroxy-10-(1h-ind; CHAETOGLOBOSINL

Molecular FormulaC32H36N2O5

Molecular Weight528.63900

Purity

Density1.3 g/cm3

Boiling Point789.7ºC at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

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Signal WordWarning

Cat. No.: 2A-1177707 Purity:
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Quality Control of [ 50335-03-0 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number50335-03-0
Catalog No.2A-1177707
Chinese Name毛壳球菌素
Synonymschaetoglobosins; Chaetoglobosin A; CHAETOGLOBOSIN A; CHAETOGLOBOSIN; CHAETOGLOBOSINB; 18-dimethyl-,(7s,13e,16s,17e,19r,21e)-ol-3-yl)-1; CHAETOGLOBOSINE; (13)cytochalasa-13,17,21-triene-1,20,23-trione,6,7-epoxy-19-hydroxy-10-(1h-ind; CHAETOGLOBOSINL
Molecular FormulaC32H36N2O5
Molecular Weight528.63900
Density1.3 g/cm3
Boiling Point789.7ºC at 760 mmHg
Storage ConditionThe warehouse is ventilated and dry at low tempera
ApplicationChaetoglobosin A is the active ingredient in Penicillium aquamarinium extract and is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets fi
SMILESCC1=CC(C)CC=CC2C3OC3(C)C(C)C3C(Cc4c[nH]c5ccccc45)NC(=O)C23C(=O)C=CC(=O)C1O
InChIInChI=1S/C32H36N2O5/c1-17-8-7-10-22-29-31(4,39-29)19(3)27-24(15-20-16-33-23-11-6-5-9-21(20)23)34-30(38)32(22,27)26(36)13-12-25(35)28(37)18(2)14-17/h5-7,9-14,16-17,19,22,24,27-29,33,37H,8,15H2,1-4H3,(H,34,38)/b10-7+,13-12+,18-14+/t17-,19-,22?,24-,27-,28+,29-,31+,32+/m0/s1
InChI KeyOUMWCYMRLMEZJH-ZDSWJECVSA-N
Hazard Symbolstransportation
BioactivityChaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Others Target Filamentous actin[1] References [1]. Knudsen PB, et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia. 2014 Jun;28(6):1289-98. Chemical & Physical Properties Density 1.3 g/cm3 Boiling Point 789.7ºC at 760 mmHg Molecular Formula C32H36N2O5 Molecular Weight 528.63900 Flash Point 431.4ºC Exact Mass 528.26200 PSA 111.79000 LogP 4.16120 Index of Refraction 1.651 InChIKey OUMWCYMRLMEZJH-ZDSWJECVSA-N SMILES CC1=CC(C)CC=CC2C3OC3(C)C(C)C3C(Cc4c[nH]c5ccccc45)NC(=O)C23C(=O)C=CC(=O)C1O
Use ofChaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration[1]. Properties Articles27 Name chaetoglobosin A Synonym More Synonyms Chaetoglobosin A Biological Activity Description Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Others Filamentous actin[1] References [1]. Knudsen PB, et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia. 2014 Jun;28(6):1289-98. Chemical & Physical Properties Molecular Formula C32H36N2O5 Exact Mass 528.26200 PSA 111.79000 LogP 4.16120 Index of Refraction 1.651 InChIKey OUMWCYMRLMEZJH-ZDSWJECVSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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