EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Tetraethyl ammonium chloride
Tetraethyl ammonium chloride structure, CAS 56-34-8

Tetraethyl ammonium chloride

CAS Number56-34-8

SynonymsTetraethyl ammonium chloride; N,N,N,N-Tetraethylammonium chloride; Tetraethylammonium chloride; TEAC; EINECS 200-267-5; Ethanaminium, N,N,N-triethyl-, chloride (1:1); MFCD00011828; N,N,N-Triethylethanaminium chloride

Molecular Formula(C2H5)4N(Cl)

Molecular Weight165.70

Purity≥98 (titration)%

Density1.08

Boiling Point

Melting Point39°C

Flash Point

Appearancepowder

EINECS200-267-5

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9016699 Purity: ≥98 (titration)%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 56-34-8 ] Purity: ≥98 (titration)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number56-34-8
Catalog No.2A-9016699
Chinese Name四乙基氯化铵
SynonymsTetraethyl ammonium chloride; N,N,N,N-Tetraethylammonium chloride; Tetraethylammonium chloride; TEAC; EINECS 200-267-5; Ethanaminium, N,N,N-triethyl-, chloride (1:1); MFCD00011828; N,N,N-Triethylethanaminium chloride
Molecular Formula(C2H5)4N(Cl)
Molecular Weight165.70
Purity≥98 (titration)
Density1.08
Melting Point39°C
Appearancepowder
Water Solubilitymethanol: 0.1 g/mL, clear, colorless
Storage ConditionThis product should be sealed and stored in a dry
ApplicationTetraethylammonium chloride is a non-selective potassium channel blocker. Tetraethylammonium chloride is a good substrate for organic cation transporters and has anti-tumor properties.
EINECS200-267-5
HTC29239000
PubChem ID24277874
MDL NumberMFCD00011828
SMILES[Cl-].CC[N+](CC)(CC)CC
InChI1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChI KeyYMBCJWGVCUEGHA-UHFFFAOYSA-M
Beilstein/REAXYS3563247
NACRES CodeNA.32
UNSPSC12352107
Hazard SymbolsTransport
Risk CodesR36/37/38
Safety DescriptionS26;S37/39
MSDSmsds/16699_1_56_34_8.pdf
BioactivityTetraethylammonium chloride is a non-selective potassium channel blocker. Tetraethylammonium chloride is a good substrate for organic cation transporter (OCTN1). Tetraethylammonium chloride antitumor properties[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel In Vitro Tetraethylammonium (0.2-60 mM; 24-72 hours; C6 and 9L glioma cells) treatment inhibits the proliferation of C6 and 9L cells in a dose- and time-dependent manner[1]. Tetraethylammonium (40 mM; 24-72 hours; C6 and 9L glioma cells) treatment significantly increases apoptosis in cells[1]. Tetraethylammonium (40 mM; 12-48 hours; C6 and 9L glioma cells) treatment significantly elevates Bax/Bcl-2 protein ratio in a time-dependent manner[1]. The generation of intracellular ROS increased in C6 and 9L cells by the addition of 20 and 40 mM Tetraethylammonium[1]. Cell Proliferation Assay[1] Cell Line: Rat C6 and 9L glioma cells Concentration: 0.2 mM, 2 mM, 20 mM, 40 mM and 60 mM Incubation Time: 24 hours, 48 hours and 72 hours Result: Inhibited the proliferation of C6 and 9L cells in a dose- and time-dependent manner. Apoptosis Analysis[1] Cell Line: Rat C6 and 9L glioma cells Concentration: 40 mM Incubation Time: 24 hours, 48 hours and 72 hours Result: Significantly increased apoptosis in cells. Western Blot Analysis[1] Cell Line: Rat C6 and 9L glioma cells Concentration: 40 mM Incubation Time: 12 hours, 24 hours, 48 hours Result: The expression of Bax was markedly increased, while that of Bcl-2 showed a decreasing trend 12, 24 and 48 h. In Vivo Tetraethylammonium (1 mM, 3 mM, and 5 mM) significantly increases the amplitude and frequency of contractility of colon and rectum from rats in longitudinal and circular direction. Tetraethylammonium at 5 mM and 15 mM concentrations shows no effect on histology of colon and rectum from rats that are administered locally with Tetraethylammonium into colon lumen from anus for 10 days[2]. References [1]. K B Yang, et al. Tetraethylammonium inhibits glioma cells via increasing production of intracellular reactive oxygen species. Chemotherapy. 2009;55(5):372-80. [2]. Zhe Li, et al. Tetraethylammonium enhances the rectal and colonic motility in rats and human in vitro. Naunyn Schmiedebergs Arch Pharmacol. 2011 Aug;384(2):147-55. Chemical & Physical Properties Density 1.08 Melting Point 39°C Molecular Formula C8H20ClN Molecular Weight 165.704 Exact Mass 165.128433 InChIKey YMBCJWGVCUEGHA-UHFFFAOYSA-M SMILES CC[N+](CC)(CC)CC.[Cl-] Storage condition Store at RT Stability Stable. Incompatible with strong oxidizing agents. Protect from moisture. Water Solubility methanol: 0.1 g/mL, clear, colorless
Use ofTetraethylammonium chloride is a non-selective potassium channel blocker. Tetraethylammonium chloride is a good substrate for organic cation transporter (OCTN1). Tetraethylammonium chloride antitumor properties[1][2]. Properties Articles77 Name tetraethylammonium chloride Synonym More Synonyms Tetraethylammonium chloride Biological Activity Description Tetraethylammonium chloride is a non-selective potassium channel blocker. Tetraethylammonium chloride is a good substrate for organic cation transporter (OCTN1). Tetraethylammonium chloride antitumor properties[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. K B Yang, et al. Tetraethylammonium inhibits glioma cells via increasing production of intracellular reactive oxygen species. Chemotherapy. 2009;55(5):372-80. [2]. Zhe Li, et al. Tetraethylammonium enhances the rectal and colonic motility in rats and human in vitro. Naunyn Schmiedebergs Arch Pharmacol. 2011 Aug;384(2):147-55. Chemical & Physical Properties Exact Mass 165.128433 InChIKey YMBCJWGVCUEGHA-UHFFFAOYSA-M SMILES CC[N+](CC)(CC)CC.[Cl-] Storage condition Store at RT Stability Stable. Incompatible with strong oxidizing agents. Protect from moisture.
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available
Related Products in Specialty Chemicals
Busulfan55-98-12A-9016688
Biguanide56-03-12A-9016689
2-(2-Aminoethyl)isothiourea dihydrobromide56-10-02A-9016694
Cystamine dihydrochloride56-17-72A-9016696
Cantharidin56-25-72A-9016698
Benzyltriethylammonium chloride56-37-12A-9016701
L-Serine56-45-12A-9016705
5-Hydroxytryptophan56-69-92A-9016711
L-Aspartic acid56-84-82A-9016715
L-Lysine56-87-12A-9016718
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA