CAS Number98717-15-8
Synonyms(2S)-N-(2,6-dimethyl-phenyl)-1-propyl-2-piperidincarboxamide hydrochloride; Ropivacaine hydrochl; piperidine-2-carboxamide hydrochloride; (S)-Ropivacaine Hydrochloride; ROPIVCACAINE HYDROCHLORIDE; L-N-n-propylpipecolic acid-2,6-xylidide hydrochloride; S-ROPIVACAINE HCL; REACTIVE YELLOW 145; (S)-N-n-propyl-(2,6)-dimethylphenyl-2-piperidine carboxamide hydrochloride; ROPIVACAINEHCL; (S)-1-propyl-2-piperidylformo-2',6'-xylidide hydrochloride; Piperidine-3-Carboxamide Hydrochloride; (S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide monohydrochloride; n-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide hydrochloride; Ropivacaine HCL; L-ropivacaine HCl; (S)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (2S)-, hydrochl
Molecular FormulaC17H27ClN2O
Molecular Weight328.88
Purity≥98 (HPLC)%
Density1.044 g/cm3
Boiling Point410.2ºC at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 98717-15-8 |
| Catalog No. | 2A-9012342 |
| Chinese Name | 盐酸罗哌卡因 |
| Synonyms | (2S)-N-(2,6-dimethyl-phenyl)-1-propyl-2-piperidincarboxamide hydrochloride; Ropivacaine hydrochl; piperidine-2-carboxamide hydrochloride; (S)-Ropivacaine Hydrochloride; ROPIVCACAINE HYDROCHLORIDE; L-N-n-propylpipecolic acid-2,6-xylidide hydrochloride; S-ROPIVACAINE HCL; REACTIVE YELLOW 145; (S)-N-n-propyl-(2,6)-dimethylphenyl-2-piperidine carboxamide hydrochloride; ROPIVACAINEHCL; (S)-1-propyl-2-piperidylformo-2',6'-xylidide hydrochloride; Piperidine-3-Carboxamide Hydrochloride; (S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide monohydrochloride; n-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide hydrochloride; Ropivacaine HCL; L-ropivacaine HCl; (S)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (2S)-, hydrochl |
| Molecular Formula | C17H27ClN2O |
| Molecular Weight | 328.88 |
| Purity | ≥98 (HPLC) |
| Density | 1.044 g/cm3 |
| Boiling Point | 410.2ºC at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8℃ |
| Application | Ropivacaine hydrochloride is an inhibitor of K2P (two-pore potassium channel) TREK-1 with an IC50 value of 402.7 μM. |
| HTC | 2933399090 |
| PubChem ID | 329823983 |
| MDL Number | MFCD00946578 |
| SMILES | O.Cl.CCCN1CCCC[C@H]1C(=O)Nc2c(C)cccc2C |
| InChI | 1S/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2/t15-;;/m0../s1 |
| InChI Key | VSHFRHVKMYGBJL-CKUXDGONSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352203 |
| MSDS | msds/12342_1_98717_15_8.pdf |
| Use of | Ropivacaine hydrochloride is an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM. Properties Name (S)-ropivacaine hydrochloride (anhydrous) Synonym More Synonyms Ropivacaine Hydrochloride Biological Activity Description Ropivacaine hydrochloride is an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Research Areas >> Neurological Disease IC50: 402.7 μM (K2P TREK-1)[1] References [1]. Shin HW, et al. The inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on K2P (two-pore domain potassium) channel TREK-1. J Anesth. 2014 Feb;28(1):81-6. [2]. Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10(1):e0117321. Chemical & Physical Properties Exact Mass 310.181183 PSA 32.34000 LogP 4.31930 InChIKey NDNSIBYYUOEUSV-RSAXXLAASA-N Storage condition 2-8℃ Safety Information HS Code 2933399090 Synthetic Route Total: 1 Page Ropivacaine CAS#:84057-95-4 Ropivacaine Hyd... CAS#:98717-15-8 propyl (1-propy... CAS#:1236222-96-0 2,6-xylidine CAS#:87-62-7 Ropivacaine Hyd... CAS#:98717-15-8 N-(2,6-Dimethyl... CAS#:65797-42-4 1-Bromopropane CAS#:106-94-5 Ropivacaine Hyd... CAS#:98717-15-8 Literature: Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 41, # 10 p. 757 - 761 Precursor & DownStream Precursor 4 CAS#:84057-95-4 Ropivacaine CAS#:87-62-7 2,6-xylidine CAS#:65797-42-4 N-(2,6-Dimethyl... CAS#:106-94-5 1-Bromopropane DownStream 2 CAS#:84057-95-4 Ropivacaine CAS#:132112-35-7 Ropivacaine hyd... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Ronilan | 50471-44-8 | 2A-0201477 |
| Ronipamil | 85247-77-4 | 2A-9012338 |
| Ropitoin | 56079-81-3 | 2A-9012339 |
| Ropivacaine | 84057-95-4 | 2A-9012340 |
| Ropivacaine hydrochloride | 132112-35-7 | 2A-9012341 |
| Roridin A | 14729-29-4 | 2A-9012343 |
| Rottlerin | 82-08-6 | 2A-9012348 |
| Roxatidine | 78273-80-0 | 2A-9012349 |
| Roxatidine acetate | 78628-28-1 | 2A-9012350 |
| Roxolonium metilsulfate | 53862-80-9 | 2A-9012352 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS