CAS Number84057-95-4
Synonyms(S)-ROPIVACAINE HCL; (2S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide; (S)-ROPIVACAINE HYDROCHLORIDE; (S)ROPIVACAINE HYDROCHLORIDE; (S)-ROPIVACAINEHYDROCHLORIDE; UNII-V910P86109; (S)-(-)-ropivacaine; (-)-1-propyl-2',6'-dimethyl-2-piperidylcarboxyanilide; Ropivacaine; Ropivacaine hydrochloride Monohydrate; (S)ROPIVACAINE HY DROCHLORIDE; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (2S)-, hydrochloride, hydrate (1:1:1); S-ROPIVACAINE HCL; Ropivacaine (hydrochloride Monohydrate); (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide; Ropivacaine API; (+-)-ropivacaine hydrochloride; (S)-ROPIVACAINEHCL; (S)-(-)-1-propyl-2',6'-pipecoloxylidide; S-ROPIVACAINEHCL; ROPACARAINEHCL; MFCD00864425; RopivacaineHcl/MesylateBase; Ropivacainehydrochloride; Naropin; Ropivaca
Molecular FormulaC17H26N2O
Molecular Weight274.40
Purity99.00%
Density1.0±0.1 g/cm3
Boiling Point410.2±45.0 °C at 760 mmHg
Melting Point144 - 146ºC
AppearanceWhite or off-white crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 84057-95-4 |
| Catalog No. | 2A-9012340 |
| Chinese Name | 罗哌卡因 |
| Synonyms | (S)-ROPIVACAINE HCL; (2S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide; (S)-ROPIVACAINE HYDROCHLORIDE; (S)ROPIVACAINE HYDROCHLORIDE; (S)-ROPIVACAINEHYDROCHLORIDE; UNII-V910P86109; (S)-(-)-ropivacaine; (-)-1-propyl-2',6'-dimethyl-2-piperidylcarboxyanilide; Ropivacaine; Ropivacaine hydrochloride Monohydrate; (S)ROPIVACAINE HY DROCHLORIDE; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (2S)-, hydrochloride, hydrate (1:1:1); S-ROPIVACAINE HCL; Ropivacaine (hydrochloride Monohydrate); (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide; Ropivacaine API; (+-)-ropivacaine hydrochloride; (S)-ROPIVACAINEHCL; (S)-(-)-1-propyl-2',6'-pipecoloxylidide; S-ROPIVACAINEHCL; ROPACARAINEHCL; MFCD00864425; RopivacaineHcl/MesylateBase; Ropivacainehydrochloride; Naropin; Ropivaca |
| Molecular Formula | C17H26N2O |
| Molecular Weight | 274.40 |
| Purity | 99.00 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 410.2±45.0 °C at 760 mmHg |
| Melting Point | 144 - 146ºC |
| Appearance | White or off-white crystalline powder |
| Water Solubility | Insoluble |
| Storage Condition | -20℃ |
| Application | Ropivacaine is a potent sodium channel blocker and can be used as a local anesthetic agent. Ropivacaine causes nerve fiber impulse conduction block by reversibly inhibiting sodium ion influx. Ropivaca |
| HTC | 2933399090 |
| MDL Number | MFCD00864425 |
| SMILES | N1([C@@H](CCCC1)C(=O)Nc2c(cccc2C)C)CCC |
| InChI | 1S/C17H26N2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1 |
| InChI Key | ZKMNUMMKYBVTFN-HNNXBMFYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/12340_1_84057_95_4.pdf |
| Use of | Properties Name (S)-ropivacaine Synonym More Synonyms Ropivacaine Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Dene Simpson, et al. Ropivacaine: a review of its use in regional anaesthesia and acute pain management. Drugs. 2005;65(18):2675-717. [2]. Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10(1):e0117321. [3]. Hye Won Shin, et al. The inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on K2P (two-pore domain potassium) channel TREK-1. J Anesth [4]. Milan Patel, et al. Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension. Life Sci. 2019 Apr 1;222:22-28. Chemical & Physical Properties Molecular Formula C17H26N2O Exact Mass 274.204498 PSA 32.34000 Index of Refraction 1.552 InChIKey ZKMNUMMKYBVTFN-HNNXBMFYSA-N Storage condition -20℃ Safety Information Hazard Codes Xi WGK Germany 3 RTECS LK8650000 HS Code 2933399090 Synthetic Route Total: 1 Page Ropivacaine Hyd... CAS#:98717-15-8 Ropivacaine CAS#:84057-95-4 1-Bromopropane CAS#:106-94-5 (S)-N-(2,6-Dime... CAS#:27262-40-4 Ropivacaine CAS#:84057-95-4 Precursor & DownStream Precursor 3 CAS#:98717-15-8 Ropivacaine Hyd... CAS#:106-94-5 1-Bromopropane CAS#:27262-40-4 (S)-N-(2,6-Dime... DownStream 2 CAS#:98717-15-8 Ropivacaine Hyd... CAS#:132112-35-7 Ropivacaine hyd... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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