CAS Number47141-42-4
SynonymsLEVOBUNOLOL; Betagan; Levobunololum; MFCD00864586; Akbeta; 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one; UNII-G6317AOI7K
Molecular FormulaC17H25NO3
Molecular Weight327.85
Purity98%
Melting Point205 - 210ºC
AppearanceWhite to pink powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 47141-42-4 |
| Catalog No. | 2A-9011164 |
| Chinese Name | 左布诺洛尔 |
| Synonyms | LEVOBUNOLOL; Betagan; Levobunololum; MFCD00864586; Akbeta; 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one; UNII-G6317AOI7K |
| Molecular Formula | C17H25NO3 |
| Molecular Weight | 327.85 |
| Purity | 98 |
| Melting Point | 205 - 210ºC |
| Appearance | White to pink powder |
| Storage Condition | -20?C Freezer, Under Inert Atmosphere |
| Application | Levobunol is a potent non-selective beta-adrenergic receptor antagonist. Levobunol is an intraocular pressure-lowering agent that reduces mean intraocular pressure (IOP). Levobunol can be used in the |
| HTC | 2922509090 |
| MDL Number | MFCD00864586 |
| SMILES | N(C[C@H](O)COc1c2c(ccc1)C(=O)CCC2)C(C)(C)C |
| InChI | 1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1 |
| InChI Key | IXHBTMCLRNMKHZ-LBPRGKRZSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/11164_1_47141_42_4.pdf |
| Use of | Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3]. Properties Name levobunolol Synonym More Synonyms LEVOBUNOLOL Biological Activity Description Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor β-adrenoceptor References [1]. Mohammadi M, et al. Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery. Acta Biomater. 2018 Jun;73:90-102. [2]. Kumar, N, et al. Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy. Futur J Pharm Sci 6, 109 (2020). [3]. Zhang M, et al. Superior oblique myokymia treated with levobunolol. J AAPOS. 2018 Feb;22(1):67-69.e2. Chemical & Physical Properties Molecular Formula C17H25NO3 Exact Mass 291.18300 PSA 58.56000 LogP 2.72430 InChIKey IXHBTMCLRNMKHZ-LBPRGKRZSA-N Storage condition -20?C Freezer, Under Inert Atmosphere Safety Information HS Code 2922509090 |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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