CAS Number35449-36-6
SynonymsGemcadiol; 2,2,9,9-tetramethyl-decane-1,10-diol; 2,2,9,9-Tetramethyl-1,10-decanediol; CI-720; 2,2,9,9-Tetramethyl-1,10-decandiol; 2,2,9,9-Tetramethyl-decan-1,10-diol
Molecular FormulaC14H30O2
Molecular Weight230.39
Purity98.00%
Density0.904g/cm3
Boiling Point319.3ºC at 760mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 35449-36-6 |
| Catalog No. | 2A-9010703 |
| Chinese Name | 1,10-Decanediol,2,2,9,9-tetramethyl |
| Synonyms | Gemcadiol; 2,2,9,9-tetramethyl-decane-1,10-diol; 2,2,9,9-Tetramethyl-1,10-decanediol; CI-720; 2,2,9,9-Tetramethyl-1,10-decandiol; 2,2,9,9-Tetramethyl-decan-1,10-diol |
| Molecular Formula | C14H30O2 |
| Molecular Weight | 230.39 |
| Purity | 98.00 |
| Density | 0.904g/cm3 |
| Boiling Point | 319.3ºC at 760mmHg |
| Application | Gelydiol is a powerful anti-fat agent. Gilidiol has the potential to study hyperlipoproteinemia [1][2]. |
| HTC | 2905399090 |
| MDL Number | MFCD00865765 |
| SMILES | CC(C)(CO)CCCCCCC(C)(C)CO |
| InChI | InChI=1S/C14H30O2/c1-13(2,11-15)9-7-5-6-8-10-14(3,4)12-16/h15-16H,5-12H2,1-4H3 |
| InChI Key | DJKWDKJYFYUEBQ-UHFFFAOYSA-N |
| MSDS | msds/10703_1_35449_36_6.pdf |
| Use of | Gemcadiol is a potent antilipemic agent. Gemcadiol has the potential for the research of hyperlipoproteinemia[1][2]. Properties Name 2,2,9,9-tetramethyldecane-1,10-diol Synonym More Synonyms 1,10-Decanediol,2,2,9,9-tetramethyl Biological Activity Description Gemcadiol is a potent antilipemic agent. Gemcadiol has the potential for the research of hyperlipoproteinemia[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease References [1]. Blumethal HP, et al. Gemcadiol: a new antilipemic drug, a clinical trial. Lipids. 1977 Jan;12(1):44-8. [2]. Fitzgerald JE, et al. Preclinical toxicology studies with the lipid-regulating agent gemcadiol. Fundam Appl Toxicol. 1986 Apr;6(3):520-31. Chemical & Physical Properties Molecular Formula C14H30O2 Exact Mass 230.22500 PSA 40.46000 LogP 3.36400 Index of Refraction 1.461 InChIKey DJKWDKJYFYUEBQ-UHFFFAOYSA-N SMILES CC(C)(CO)CCCCCCC(C)(C)CO Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1,10-Decanediol, 2,2,9,9-tetramethyl- CAS REGISTRY NUMBER : 35449-36-6 BEILSTEIN REFERENCE NO. : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C14-H30-O2 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : Q1X1&1&6X1&1&1Q HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,520,1986 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0064286 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,520,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Blood - pigmented or nucleated red blood cells Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,520,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,520,1986 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,520,1986 Safety Information HS Code 2905399090 Synthetic Route Total: 1 Page 2,2,9,9-tetrame... CAS#:22092-62-2 1,10-Decanediol... CAS#:35449-36-6 Literature: Adams; Anderson Journal of the American Chemical Society, 1951 , vol. 73, p. 136,141 CAS#:22092-67-7 1,10-Decanediol... CAS#:35449-36-6 Literature: Adams; Anderson Journal of the American Chemical Society, 1951 , vol. 73, p. 136,141 CAS#:158300-02-8 1,10-Decanediol... CAS#:35449-36-6 Literature: Adams; Anderson Journal of the American Chemical Society, 1951 , vol. 73, p. 136,141 Precursor & DownStream Precursor 1 CAS#:22092-62-2 2,2,9,9-tetrame... DownStream 0 |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Gardenoside | 24512-62-7 | 2A-9010696 |
| Gastric mucin | 53-46-3 | 2A-9010697 |
| Geclosporin | 74436-00-3 | 2A-9010699 |
| Gedocarnil | 109623-97-4 | 2A-9010700 |
| Geldanamycin | 30562-34-6 | 2A-9010702 |
| Gemifioxacin mesylate | 210353-53-0 | 2A-9010707 |
| Geneticin | 49863-47-0 | 2A-9010709 |
| Genipin | 6902-77-8 | 2A-9010710 |
| Geniposide | 24512-63-8 | 2A-9010711 |
| Geniposidic acid | 27741-01-1 | 2A-9010712 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS