CAS Number53-46-3
Synonymsasabaine; Methanthelinium bromide; mtb51; diethyl-methyl-[2-(xanthene-9-carbonyloxy)-ethyl]-ammonium,bromide; sc2910; ulcine; N,N-diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]-ethanaminium; methanthelinium bromide; banthin; Diaethyl-methyl-[2-(xanthen-9-carbonyloxy)-aethyl]-ammonium,Bromid; avagal; Ulcine Bromide; methantheline bromide; doladene; metaxan; banthine; vagamin
Molecular FormulaC21H26BrNO3
Molecular Weight420.34000
Purity98.00%
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 53-46-3 |
| Catalog No. | 2A-9010697 |
| Chinese Name | 溴甲胺太林 |
| Synonyms | asabaine; Methanthelinium bromide; mtb51; diethyl-methyl-[2-(xanthene-9-carbonyloxy)-ethyl]-ammonium,bromide; sc2910; ulcine; N,N-diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]-ethanaminium; methanthelinium bromide; banthin; Diaethyl-methyl-[2-(xanthen-9-carbonyloxy)-aethyl]-ammonium,Bromid; avagal; Ulcine Bromide; methantheline bromide; doladene; metaxan; banthine; vagamin |
| Molecular Formula | C21H26BrNO3 |
| Molecular Weight | 420.34000 |
| Purity | 98.00 |
| HTC | 2932999099 |
| MDL Number | MFCD00213000 |
| SMILES | CC[N+](C)(CC)CCOC(=O)C1c2ccccc2Oc2ccccc21.[Br-] |
| InChI | InChI=1S/C21H26NO3.BrH/c1-4-22(3,5-2)14-15-24-21(23)20-16-10-6-8-12-18(16)25-19-13-9-7-11-17(19)20;/h6-13,20H,4-5,14-15H2,1-3H3;1H/q+1;/p-1 |
| InChI Key | PQMWYJDJHJQZDE-UHFFFAOYSA-M |
| NACRES Code | NA.41 |
| UNSPSC | 12352203 |
| MSDS | msds/10697_1_53_46_3.pdf |
| Use of | Methantheline Bromide is a synthetic antispasmodic. It is used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems. Properties Synonym More Synonyms Chemical & Physical Properties Molecular Formula C21H26BrNO3 Exact Mass 419.11000 PSA 35.53000 LogP 0.95780 InChIKey PQMWYJDJHJQZDE-UHFFFAOYSA-M Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Ammonium, diethyl(2-hydroxyethyl)methyl-, bromide, xanthene-9-carboxylate CAS REGISTRY NUMBER : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C21-H26-N-O3.Br MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T C666 BO IHJ IVO2K2&2&1 &Q &E HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4800 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,391,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,357,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,107,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4300 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,221,1956 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Kidney, Ureter, Bladder - interstitial nephritis Related to Chronic Data - death REFERENCE : Safety Information RIDADR NONH for all modes of transport HS Code 2932999099 Synthetic Route Total: 1 Page Methyl bromide CAS#:74-83-9 9H-Xanthene-9-c... CAS#:24539-72-8 Methantheline B... CAS#:53-46-3 Literature: US2659732 , ; DE948333 , ; Xanthene-9-carb... CAS#:82-07-5 Methantheline B... CAS#:53-46-3 Literature: Pharmaceutical Bulletin, , vol. 3, p. 417,420 Precursor & DownStream Precursor 3 CAS#:74-83-9 Methyl bromide CAS#:24539-72-8 9H-Xanthene-9-c... CAS#:82-07-5 Xanthene-9-carb... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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