CAS Number525-21-3
SynonymsEINECS 208-370-7; 8-hydroxy-6,7,-dimethoxycoumarin; 8-Hydroxy-6,7-dimethoxy-cumarin; 6,7-dimethoxy-8-hydroxy-2H-1-benzopyran-2-one; 8-hydroxy-6,7-dimethoxy-2-benzopyrone; 6,7-dimethoxy-8-hydroxycoumarin; 8-Hydroxy-6,7-dimethoxy-2H-chromen-2-one; Fraxidin; 6,7,8-Trihydroxycoumarin 6,7-dimethyl ether
Molecular FormulaC11H10O5
Molecular Weight236.22
Purity≥90 (LC/MS-ELSD)%
Density1.4±0.1 g/cm3
Boiling Point424.2±45.0 °C at 760 mmHg
Melting Point196-197ºC
Appearancesolid
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 525-21-3 |
| Catalog No. | 2A-9010630 |
| Chinese Name | 嗪皮啶 |
| Synonyms | EINECS 208-370-7; 8-hydroxy-6,7,-dimethoxycoumarin; 8-Hydroxy-6,7-dimethoxy-cumarin; 6,7-dimethoxy-8-hydroxy-2H-1-benzopyran-2-one; 8-hydroxy-6,7-dimethoxy-2-benzopyrone; 6,7-dimethoxy-8-hydroxycoumarin; 8-Hydroxy-6,7-dimethoxy-2H-chromen-2-one; Fraxidin; 6,7,8-Trihydroxycoumarin 6,7-dimethyl ether |
| Molecular Formula | C11H10O5 |
| Molecular Weight | 236.22 |
| Purity | ≥90 (LC/MS-ELSD) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 424.2±45.0 °C at 760 mmHg |
| Melting Point | 196-197ºC |
| Appearance | solid |
| Storage Condition | 2-8℃, dry, sealed |
| Application | Fraxidin is a coumarin isolated from the roots of Jatropha podagrica and has antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 µg/disk. |
| HTC | 2932209090 |
| MDL Number | MFCD00145039 |
| SMILES | [o]1c2c(cc[c]1=O)cc(c(c2OC)OC)OC |
| InChI | 1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3 |
| InChI Key | RAYQKHLZHPFYEJ-UHFFFAOYSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12352205 |
| MSDS | msds/10630_1_525_21_3.pdf |
| Use of | Properties Name 8-hydroxy-6,7-dimethoxychromen-2-one Synonym More Synonyms Fraxidin Biological Activity Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial Bacillus subtilis[2] References [1]. Kim NY, et al. In vitro inducible nitric oxide synthesis inhibitory active constituents from Fraxinus rhynchophylla. Planta Med. 1999 Oct;65(7):656-8. [2]. Minh TN, et al. Isolation and Purification of Bioactive Compounds from the Stem Bark of Jatropha podagrica. Molecules. 2019 Mar 3;24(5). pii: E889. Chemical & Physical Properties Molecular Formula C11H10O5 Exact Mass 222.052826 PSA 68.90000 Index of Refraction 1.588 InChIKey QNFBKOHHLAWWTC-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2932209090 Synthetic Route 8-acetyl-6,7-di... CAS#:263271-48-3 CAS#:525-21-3 Literature: Ahluwalia et al. Tetrahedron, 1959 , vol. 5, p. 90 fraxidin 8-O-β-... CAS#:58970-71-1 D-glucopyranose CAS#:2280-44-6 CAS#:525-21-3 Literature: Tsukamoto; Hisada; Nishibe Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 4069 - 4073 diazomethane CAS#:186581-53-3 CAS#:525-21-3 Literature: Wessely; Demmer Chemische Berichte, 1929 , vol. 62, p. 126 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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