| Chemical & Physical Properties | |
|---|---|
| CAS Number | 26130-02-9 |
| Catalog No. | 2A-9010632 |
| Chinese Name | 夫仑替唑 |
| Synonyms | FRENTIZOLE; 1-(6-methoxybenzo[d]thiazol-2-yl)-3-phenylurea; 1-(6-methoxy-2-benzothiazolyl)-3-phenylurea; Frentizol; 1-(6-methoxy-benzothiazol-2-yl)-3-phenyl-urea |
| Molecular Formula | C15H13N3O2S |
| Molecular Weight | 299.35 |
| Purity | 98.00 |
| Density | 1.42g/cm3 |
| Storage Condition | 2-8℃ |
| Application | Frentizole is an FDA-approved immunosuppressant and a new Aβ-ABAD interaction inhibitor. |
| HTC | 2934999090 |
| MDL Number | C15H13N3O2S |
| SMILES | COc1ccc2nc(NC(=O)Nc3ccccc3)sc2c1 |
| InChI | InChI=1S/C15H13N3O2S/c1-20-11-7-8-12-13(9-11)21-15(17-12)18-14(19)16-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19) |
| InChI Key | JHBWYQRKOUBPCA-UHFFFAOYSA-N |
| MSDS | msds/10632_1_26130_02_9.pdf |
| Use of | Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.IC50 value:Target: Aβ-ABAD interaction Properties Name 1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea Synonym More Synonyms Frentizole Biological Activity Description Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.IC50 value:Target: Aβ-ABAD interaction Related Catalog Signaling Pathways >> Neuronal Signaling >> Amyloid-β Research Areas >> Inflammation/Immunology References [1]. I I Scheetz ME, D G Carlson, and M R Schinitsky Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus. Infec [2]. Hatfield SM, Hartley LW, Schmidtke JR. The immunomodulatory action of frentizole, a novel immunosuppressive agent. Immunopharmacology. 1982 Dec;5(2):169-79. [3]. Xie, Yuli; Deng, Shixian; Chen, Zhenzhang et al. Identification of small-molecule inhibitors of the Aβ-ABAD interaction. Bioorganic & Medicinal Chemistry Letters (2006), 16(17), 4657-4660. Chemical & Physical Properties Molecular Formula C15H13N3O2S Exact Mass 299.07300 PSA 94.98000 LogP 4.03550 Index of Refraction 1.752 InChIKey JHBWYQRKOUBPCA-UHFFFAOYSA-N Storage condition 2-8℃ Safety Information HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Forskolin | 66575-29-9 | 2A-9010610 |
| Fortimicin | 55779-06-1 | 2A-9010611 |
| Fotemustine | 92118-27-9 | 2A-9010626 |
| Fradafiban | 148396-36-5 | 2A-9010627 |
| Fraxidin | 525-21-3 | 2A-9010630 |
| Friedelin | 559-74-0 | 2A-9010633 |
| Fronepidil | 79700-63-3 | 2A-9010634 |
| Fropenem | 106560-14-9 | 2A-9010635 |
| Fructose-1,6-diphosphate magnesium salt | 2A-301720 | 2A-9010637 |
| Fructus cannabis PE | 2A-301722 | 2A-9010639 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS