CAS Number3650-09-7
SynonymsSalvin; Carnosic acid; RoseOx; 11,12-Dihydroxyabieta-8,11,13-trien-20-oic acid; MFCD02259459; Carsonic acid; Carnosolic Acid
Molecular FormulaC20H28O4
Molecular Weight332.43
Purity≥91%
Density1.2±0.1 g/cm3
Boiling Point506.4±50.0 °C at 760 mmHg
Melting Point190 °C
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3650-09-7 |
| Catalog No. | 2A-9009600 |
| Chinese Name | 鼠尾草酸 |
| Synonyms | Salvin; Carnosic acid; RoseOx; 11,12-Dihydroxyabieta-8,11,13-trien-20-oic acid; MFCD02259459; Carsonic acid; Carnosolic Acid |
| Molecular Formula | C20H28O4 |
| Molecular Weight | 332.43 |
| Purity | ≥91 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 506.4±50.0 °C at 760 mmHg |
| Melting Point | 190 °C |
| Appearance | powder |
| Storage Condition | Sealed in a cool, dry environment |
| Application | Carnosic acid can inhibit oxidative stress and inflammation, inhibit cell proliferation, and has antibacterial activity. |
| PubChem ID | 329774804 |
| MDL Number | MFCD02259459 |
| SMILES | CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(O)=O)c2c(O)c1O |
| InChI | 1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1 |
| InChI Key | QRYRORQUOLYVBU-VBKZILBWSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12352106 |
| Hazard Symbols | Transport |
| MSDS | msds/9600_1_3650_09_7.pdf |
| Bioactivity | Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Cancer Natural Products >> Terpenoids and Glycosides In Vitro Carnosic acid, a phenolic diterpene, is enriched in the leaves of Lamiaceae plants, and is particularly high in dried leaves of Rosmarinus officinalis L. and Salvia officinalis. Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. It is widely reported that Carnosic acid has a therapeutic potential in different types of cancer, mostly based on in vitro experiments. Carnosic acid has also shown neuroprotective effects in experimental models of neurodegenerative diseases, mainly through activation of the antioxidant NRF2/ARE pathway[1]. References [1]. Yesil-Celiktas O, et al. Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines. Plant Foods Hum Nutr. 2010 Jun;65(2):158-63. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 506.4±50.0 °C at 760 mmHg Melting Point 190 °C Molecular Formula C20H28O4 Molecular Weight 332.434 Flash Point 274.2±26.6 °C Exact Mass 332.198761 PSA 77.76000 LogP 4.93 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.576 InChIKey QRYRORQUOLYVBU-VBKZILBWSA-N SMILES CC(C)c1cc2c(c(O)c1O)C1(C(=O)O)CCCC(C)(C)C1CC2 Storage condition −20°C |
| Use of | Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. Properties Articles18 Name carnosic acid Synonym More Synonyms Carnosic acid Biological Activity Description Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Cancer Natural Products >> Terpenoids and Glycosides References [1]. Yesil-Celiktas O, et al. Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines. Plant Foods Hum Nutr. 2010 Jun;65(2):158-63. Chemical & Physical Properties Molecular Formula C20H28O4 Exact Mass 332.198761 PSA 77.76000 Index of Refraction 1.576 InChIKey QRYRORQUOLYVBU-VBKZILBWSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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