CAS Number34450-18-5
SynonymsOctadec-17-ynoic acid; 17-Octadecynoic acid; MFCD00077382
Molecular FormulaC18H32O2
Molecular Weight280.45
Purity≥95 (GC)%
Density0.9±0.1 g/cm3
Boiling Point400.8±18.0 °C at 760 mmHg
Melting Point142-148 °C(lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 34450-18-5 |
| Catalog No. | 2A-9094097 |
| Chinese Name | 17-十八炔酸 |
| Synonyms | Octadec-17-ynoic acid; 17-Octadecynoic acid; MFCD00077382 |
| Molecular Formula | C18H32O2 |
| Molecular Weight | 280.45 |
| Purity | ≥95 (GC) |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 400.8±18.0 °C at 760 mmHg |
| Melting Point | 142-148 °C(lit.) |
| Appearance | powder |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | Alkynyl Stearic Acid is a PROTAC linker and belongs to the alkyl chain class. Can be used to synthesize PROTAC molecules. |
| HTC | 2916190090 |
| PubChem ID | 24898058 |
| MDL Number | MFCD00077382 |
| SMILES | C#CCCCCCCCCCCCCCCCC(O)=O |
| InChI | 1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20) |
| InChI Key | DZIILFGADWDKMF-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352106 |
| Hazard Symbols | transportation |
| MSDS | msds/94097_1_34450_18_5.pdf |
| Bioactivity | Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target Alkyl-Chain In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 0.9±0.1 g/cm3 Boiling Point 400.8±18.0 °C at 760 mmHg Melting Point 142-148 °C(lit.) Molecular Formula C18H32O2 Molecular Weight 280.445 Flash Point 194.7±15.9 °C Exact Mass 280.240234 PSA 37.30000 LogP 6.86 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.470 InChIKey DZIILFGADWDKMF-UHFFFAOYSA-N SMILES C#CCCCCCCCCCCCCCCCC(=O)O Storage condition Store at RT |
| Use of | Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Articles33 Name 17-Octadecynoic acid Synonym More Synonyms 17-ODYA Biological Activity Description Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl-Chain In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C18H32O2 Exact Mass 280.240234 PSA 37.30000 Index of Refraction 1.470 InChIKey DZIILFGADWDKMF-UHFFFAOYSA-N SMILES C#CCCCCCCCCCCCCCCCC(=O)O Storage condition Store at RT |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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