CAS Number84687-43-4
SynonymsAstragalus Polysaccharides; ASTRAGALOSIDE; Astrasieversianin XIV; Astragalus extract; Astragaloside IV; cyclosieversioside F; cyclosiversioside F; MFCD07368617
Molecular FormulaC41H68O14
Molecular Weight784.97
Purity98%
Density1.4±0.1 g/cm3
Boiling Point895.7±65.0 °C at 760 mmHg
Melting Point295-296 °C (lit.)
AppearanceSolid;White to Almost white powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 84687-43-4 |
| Catalog No. | 2A-9009255 |
| Chinese Name | 黄芪甲苷IV |
| Synonyms | Astragalus Polysaccharides; ASTRAGALOSIDE; Astrasieversianin XIV; Astragalus extract; Astragaloside IV; cyclosieversioside F; cyclosiversioside F; MFCD07368617 |
| Molecular Formula | C41H68O14 |
| Molecular Weight | 784.97 |
| Purity | 98 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 895.7±65.0 °C at 760 mmHg |
| Melting Point | 295-296 °C (lit.) |
| Appearance | Solid;White to Almost white powder to crystal |
| Storage Condition | -20°C; store under inert gas; avoid moisture (hygr |
| Application | Astragaloside IV is a saponin isolated from Astragalus membranaceus, which can inhibit the activation of ERK1/2 and JNK. In breast cancer cells MDA-MB-231, it can downregulate the (MMP)-2 and (MMP)-9 |
| HTC | 2932999099 |
| PubChem ID | 329749074 |
| MDL Number | MFCD16036240 |
| SMILES | CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O |
| InChI | 1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1 |
| InChI Key | QMNWISYXSJWHRY-YLNUDOOFSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/9255_1_84687_43_4.pdf |
| Use of | Properties Articles31 Name Astragaloside IV Synonym More Synonyms Astragaloside IV Biological Activity Related Catalog Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK Signaling Pathways >> MAPK/ERK Pathway >> JNK Signaling Pathways >> Metabolic Enzyme/Protease >> MMP Natural Products >> Terpenoids and Glycosides Research Areas >> Cancer References [1]. Li M, et al. Astragaloside IV attenuates cognitive impairments induced by transient cerebral ischemia and reperfusion in mice via anti-inflammatory mechanisms. Neurosci Lett. 2016 Dec 20. pii: S0304-3940(16)30994-6 [3]. Liu L, et al. [Protective effect of astragaloside IV against acute liver failure in experimental mice]. Zhonghua Gan Zang Bing Za Zhi. 2016 Oct 20;24(10):772-777. Chemical & Physical Properties Molecular Formula C41H68O14 Exact Mass 784.460938 PSA 228.22000 Index of Refraction 1.621 InChIKey QMNWISYXSJWHRY-YLNUDOOFSA-N Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter RIDADR NONH for all modes of transport HS Code 2932999099 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Asimadoline | 153205-46-0 | 2A-9009247 |
| Asocainol | 77400-65-8 | 2A-9009248 |
| Asparagus Root P.E. | 2A-300332 | 2A-9009249 |
| Aspidospermine | 466-49-9 | 2A-9009250 |
| Astemisinin | 63968-64-9 | 2A-9009252 |
| Atiprosine | 89303-63-9 | 2A-9009257 |
| Atovaquone | 95233-18-4 | 2A-9009261 |
| Atropine | 51-55-8 | 2A-9009263 |
| Atropine sulfate monohydrate | 5908-99-6 | 2A-9009264 |
| Aurantiol | 89-43-0 | 2A-9009266 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS