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Altrenogest structure, CAS 850-52-2

Altrenogest

CAS Number850-52-2

Synonyms(17b)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; 13b-Methyl-17a-allyl-D4,9,11-gonatriene-17b-ol-3-one; (17β)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; Allyltrenbolone; r2267; 17α-Allyl-17-hydroxyestra-4,9,11-trien-3-one; altregonest; (17β)-17-hydroxy-17-(prop-2-en-1-yl)estra-4,9,11-trien-3-one; Altrenogest; REGU-MATE; 17-allyltrenbolone; ru2267; drc6246; Regumate; 17a-Allyl-17-hydroxyestra-4,9,11-trien-3-one

Molecular FormulaC21H26O2

Molecular Weight310.44

Purity98%

Density1.1±0.1 g/cm3

Boiling Point495.6±45.0 °C at 760 mmHg

Melting Point120ºC

Flash Point

AppearanceSolid;White to Yellow powder to crystal

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Cat. No.: 2A-9009137 Purity: 98%
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Quality Control of [ 850-52-2 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number850-52-2
Catalog No.2A-9009137
Chinese Name烯丙孕素
Synonyms(17b)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; 13b-Methyl-17a-allyl-D4,9,11-gonatriene-17b-ol-3-one; (17β)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; Allyltrenbolone; r2267; 17α-Allyl-17-hydroxyestra-4,9,11-trien-3-one; altregonest; (17β)-17-hydroxy-17-(prop-2-en-1-yl)estra-4,9,11-trien-3-one; Altrenogest; REGU-MATE; 17-allyltrenbolone; ru2267; drc6246; Regumate; 17a-Allyl-17-hydroxyestra-4,9,11-trien-3-one
Molecular FormulaC21H26O2
Molecular Weight310.44
Purity98
Density1.1±0.1 g/cm3
Boiling Point495.6±45.0 °C at 760 mmHg
Melting Point120ºC
AppearanceSolid;White to Yellow powder to crystal
Storage ConditionThe warehouse is ventilated and dried at low tempe
ApplicationAltrenogest (A35957; RU2267) is a progesterone, structurally related to trenbolone, and can act on progesterone receptors.
HTC2937290090
MDL NumberMFCD00867855
SMILESC=CCC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C=CC21C
InChIInChI=1S/C21H26O2/c1-3-10-21(23)12-9-19-18-6-4-14-13-15(22)5-7-16(14)17(18)8-11-20(19,21)2/h3,8,11,13,18-19,23H,1,4-7,9-10,12H2,2H3
InChI KeyVWAUPFMBXBWEQY-ANULTFPQSA-N
MSDSmsds/9137_1_850_52_2.pdf
Use ofAltrenogest(A35957; RU2267) is a progestogen structurally related to veterinary steroid trenbolone.Target: Progesterone ReceptorAltrenogest is a progestogen structurally related to veterinary steroid trenbolone. Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal dysfunction [1]. The oil and gel altrenogest preparations are equally effective in modulating estrous behavior and time to estrus and ovulation. Altrenogest treatment started late in diestrus appears to result in a high incidence of ovulation during treatment and when luteolysis and ovulation occur during treatment; the subsequent luteal phase is frequently prolonged due to failure of regression of the CL [2]. Properties Name Altrenogest Synonym More Synonyms Altrenogest Biological Activity Description Altrenogest(A35957; RU2267) is a progestogen structurally related to veterinary steroid trenbolone.Target: Progesterone ReceptorAltrenogest is a progestogen structurally related to veterinary steroid trenbolone. Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal dysfunction [1]. The oil and gel altrenogest preparations are equally effective in modulating estrous behavior and time to estrus and ovulation. Altrenogest treatment started late in diestrus appears to result in a high incidence of ovulation during treatment and when luteolysis and ovulation occur during treatment; the subsequent luteal phase is frequently prolonged due to failure of regression of the CL [2]. Related Catalog Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology References [1]. Parry-Weeks, L.C. and D.W. Holtan, Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients. J Reprod Fertil Suppl, 1987. 35: p. 433-8. [2]. Daels, P.F., et al., Persistence of the luteal phase following ovulation during altrenogest treatment in mares. Theriogenology, 1996. 46(5): p. 799-811. Chemical & Physical Properties Molecular Formula C21H26O2 Exact Mass 310.193268 PSA 37.30000 Index of Refraction 1.594 InChIKey VWAUPFMBXBWEQY-ANULTFPQSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Estra-4,9,11-trien-3-one, 17-alpha-allyl-17-hydroxy- CAS REGISTRY NUMBER : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C21-H26-O2 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : L E5 B666 OV AU CU MUTJ E1 FQ F2U1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 18 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : THGNBO Theriogenology. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1974- Volume(issue)/page/year: 16,195,1981 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : 2500 ug/kg SEX/DURATION : female 10 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 70,1357,1992 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 15 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Maternal Effects - other effects REFERENCE : JRFSAR Journal of Reproduction and Fertility, Supplement. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) No.1- 1966- Volume(issue)/page/year: 32,193,1982 Safety Information WGK Germany 3.0 RTECS KG7745000 HS Code 2937290090
Transport InfoProduct name: Tetraestrone (allylgestin)
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