CAS Number89796-99-6
SynonymsAcelofenac; Aceclofenac; EINECS 205-783-4; Aceclofar; Preservex; MFCD00864296; Falcol; (2-{2-[(2,6-Dichlorophenyl)amino]phenyl}acetoxy)acetic acid; Tresquim; Biofenac; Zerodol; Airtal; Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester; Gerbin
Molecular FormulaC16H13Cl2NO4
Molecular Weight354.18
Purity≥98 (HPLC)%
Density1.5±0.1 g/cm3
Boiling Point486.0±45.0 °C at 760 mmHg
Melting Point149-153°C
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 89796-99-6 |
| Catalog No. | 2A-9009033 |
| Chinese Name | 醋氯芬酸 |
| Synonyms | Acelofenac; Aceclofenac; EINECS 205-783-4; Aceclofar; Preservex; MFCD00864296; Falcol; (2-{2-[(2,6-Dichlorophenyl)amino]phenyl}acetoxy)acetic acid; Tresquim; Biofenac; Zerodol; Airtal; Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester; Gerbin |
| Molecular Formula | C16H13Cl2NO4 |
| Molecular Weight | 354.18 |
| Purity | ≥98 (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 486.0±45.0 °C at 760 mmHg |
| Melting Point | 149-153°C |
| Appearance | powder |
| Storage Condition | -20°C Freezer |
| Packaging | III |
| Application | Aceclofenac is an analogue of the nonsteroidal anti-inflammatory compound Diclofenac. |
| HTC | 2922509090 |
| PubChem ID | 329771021 |
| MDL Number | MFCD00864296 |
| SMILES | OC(=O)COC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl |
| InChI | 1S/C16H13Cl2NO4/c17-11-5-3-6-12(18)16(11)19-13-7-2-1-4-10(13)8-15(22)23-9-14(20)21/h1-7,19H,8-9H2,(H,20,21) |
| InChI Key | MNIPYSSQXLZQLJ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | 6.1 |
| MSDS | msds/9033_1_89796_99_6.pdf |
| Bioactivity | Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.Target: COXAceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac [1]. Related Catalog Research Areas >> Inflammation/Immunology Target COX-2:3 μM (IC50) COX-1:7.3 μM (IC50) References [1]. Dannhardt G, et al. In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs). Inflamm Res. 2001 May;50(5):262-9. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 486.0±45.0 °C at 760 mmHg Melting Point 149-153°C Molecular Formula C16H13Cl2NO4 Molecular Weight 354.185 Flash Point 247.8±28.7 °C Exact Mass 353.022156 PSA 75.63000 LogP 4.16 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.639 InChIKey MNIPYSSQXLZQLJ-UHFFFAOYSA-N SMILES O=C(O)COC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Storage condition -20°C Freezer |
| Use of | Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.Target: COXAceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac [1]. Properties Articles37 Name aceclofenac Synonym More Synonyms Aceclofenac Biological Activity Description Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.Target: COXAceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac [1]. Related Catalog Research Areas >> Inflammation/Immunology COX-2:3 μM (IC50) COX-1:7.3 μM (IC50) References [1]. Dannhardt G, et al. In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs). Inflamm Res. 2001 May;50(5):262-9. Chemical & Physical Properties Exact Mass 353.022156 PSA 75.63000 Index of Refraction 1.639 InChIKey MNIPYSSQXLZQLJ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: Item 1 Poisons. UN number: 2811 Proper Shipping Name: Toxic Solid, Organic, Not Otherwise Specified Packing grade: III |
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