CAS Number70024-40-7
SynonymsTerazosin Hydrochloride Dihydrate; Terazosin monohydrochloride dihydrate; MFCD00941408; Terazosin HCl
Molecular FormulaC19H30ClN5O6
Molecular Weight459.92
Purity98%
Boiling Point664.5ºC at 760 mmHg
Melting Point215 - 217ºC
AppearanceWhite or off-white crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 70024-40-7 |
| Catalog No. | 2A-9008777 |
| Chinese Name | 盐酸特拉唑嗪二水物 |
| Synonyms | Terazosin Hydrochloride Dihydrate; Terazosin monohydrochloride dihydrate; MFCD00941408; Terazosin HCl |
| Molecular Formula | C19H30ClN5O6 |
| Molecular Weight | 459.92 |
| Purity | 98 |
| Boiling Point | 664.5ºC at 760 mmHg |
| Melting Point | 215 - 217ºC |
| Appearance | White or off-white crystalline powder |
| Storage Condition | 2-8°C |
| Application | Terazosin hydrochloride dihydrate is a selective antagonist of α-1 adrenergic receptors and can act on benign prostatic hyperplasia. |
| MDL Number | MFCD00941408 |
| SMILES | O.O.Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4 |
| InChI | 1S/C19H25N5O4.ClH.2H2O/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;;;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H;2*1H2 |
| InChI Key | NZMOFYDMGFQZLS-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/8777_1_70024_40_7.pdf |
| Bioactivity | Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR [1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Endocrinology References [1]. Kyncl, J.J., Pharmacology of terazosin: an alpha 1-selective blocker. J Clin Pharmacol, 1993. 33(9): p. 878-83. Chemical & Physical Properties Boiling Point 664.5ºC at 760 mmHg Melting Point 215 - 217ºC Molecular Formula C19H30ClN5O6 Molecular Weight 459.924 Exact Mass 459.188446 PSA 121.50000 LogP 2.31430 InChIKey NZMOFYDMGFQZLS-UHFFFAOYSA-N SMILES COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.Cl.O.O Storage condition 2-8°C |
| Use of | Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR [1]. Properties Articles26 Name terazosin hydrochloride dihydrate Synonym More Synonyms Terazosin hydrochloride dihydrate Biological Activity Description Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR [1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Endocrinology References [1]. Kyncl, J.J., Pharmacology of terazosin: an alpha 1-selective blocker. J Clin Pharmacol, 1993. 33(9): p. 878-83. Chemical & Physical Properties Exact Mass 459.188446 PSA 121.50000 LogP 2.31430 InChIKey NZMOFYDMGFQZLS-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
| Related Products in API & Advanced Intermediates | ||
|---|---|---|
| Phenyl-D5-7-hydroxywarfarin | 94820-65-2 | 2A-9008670 |
| Prednisolone sodium phosphate | 125-02-0 | 2A-9008691 |
| Prednisolone succinate | 2920-86-7 | 2A-9008692 |
| Ropinirole hydrochloride | 91374-20-8 | 2A-9008728 |
| Rosiglitazone maleate | 155141-29-0 | 2A-9008729 |
| Testosterone | 58-22-0 | 2A-9008796 |
| Testosterone cypionate | 58-20-8 | 2A-9008797 |
| Testosterone decanoate | 5721-91-5 | 2A-9008798 |
| Testosterone enanthate | 315-37-7 | 2A-9008799 |
| Testosterone isocapronate | 15267-86-9 | 2A-9008800 |
| Browse all API & Advanced Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS