CAS Number132907-72-3
Synonyms(1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanonhydrochlorid; Ramosetron HCl; Nasea; Ramosetron Hydrochloride; (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone hydrochloride (1:1); (R)-(1-Methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-6-yl)methanone hydrochloride; (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone hydrochloride; MFCD00894748; YM060; Ramosetron (Hydrochloride)
Molecular FormulaC17H18ClN3O
Molecular Weight315.80
Purity≥98 (HPLC)%
Boiling Point579.7ºC at 760mmHg
Melting Point244-246°C
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 132907-72-3 |
| Catalog No. | 2A-9008726 |
| Chinese Name | 盐酸雷莫司琼 |
| Synonyms | (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanonhydrochlorid; Ramosetron HCl; Nasea; Ramosetron Hydrochloride; (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone hydrochloride (1:1); (R)-(1-Methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-6-yl)methanone hydrochloride; (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone hydrochloride; MFCD00894748; YM060; Ramosetron (Hydrochloride) |
| Molecular Formula | C17H18ClN3O |
| Molecular Weight | 315.80 |
| Purity | ≥98 (HPLC) |
| Boiling Point | 579.7ºC at 760mmHg |
| Melting Point | 244-246°C |
| Appearance | powder |
| Storage Condition | Hygroscopic, Refrigerator, Under Inert Atmosphere |
| HTC | 2933990090 |
| SMILES | Cl.[n]1(c2c(c(c1)C(=O)[C@@H]3CCc4nc[nH]c4C3)cccc2)C |
| InChI | 1S/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1 |
| InChI Key | XIXYTCLDXQRHJO-RFVHGSKJSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | Transport |
| MSDS | msds/8726_1_132907_72_3.pdf |
| Bioactivity | Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.Target: 5-HT3 ReceptorRamosetron hydrochloride selectively blocks serotonin receptors (5-HT3). Serotonin plays a vital role in vomiting, serotonin-induced bradycardic reflex and peristalsis. The pharmacological action of Ramosetron hydrochloride is sustained and potent. Related Catalog Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Neurological Disease References [1]. http://www.drugsupdate.com/generic/view/1111 Chemical & Physical Properties Boiling Point 579.7ºC at 760mmHg Melting Point 244-246°C Molecular Formula C17H18ClN3O Molecular Weight 315.797 Flash Point 304.4ºC Exact Mass 315.113831 PSA 50.68000 LogP 3.69120 Vapour Pressure 1.96E-13mmHg at 25°C InChIKey XIXYTCLDXQRHJO-RFVHGSKJSA-N SMILES Cl.Cn1cc(C(=O)C2CCc3nc[nH]c3C2)c2ccccc21 Storage condition Hygroscopic, Refrigerator, Under Inert Atmosphere |
| Use of | Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.Target: 5-HT3 ReceptorRamosetron hydrochloride selectively blocks serotonin receptors (5-HT3). Serotonin plays a vital role in vomiting, serotonin-induced bradycardic reflex and peristalsis. The pharmacological action of Ramosetron hydrochloride is sustained and potent. Properties Articles26 Name Ramosetron Hydrochloride Synonym More Synonyms Ramosetron Hydrochloride Biological Activity Description Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.Target: 5-HT3 ReceptorRamosetron hydrochloride selectively blocks serotonin receptors (5-HT3). Serotonin plays a vital role in vomiting, serotonin-induced bradycardic reflex and peristalsis. The pharmacological action of Ramosetron hydrochloride is sustained and potent. Related Catalog Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Neurological Disease References [1]. http://www.drugsupdate.com/generic/view/1111 Chemical & Physical Properties Exact Mass 315.113831 PSA 50.68000 LogP 3.69120 InChIKey XIXYTCLDXQRHJO-RFVHGSKJSA-N Storage condition Hygroscopic, Refrigerator, Under Inert Atmosphere |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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