CAS Number2934-97-6
SynonymsBerberine,tetrahydro; d,l-tetrahydropalmatine; (S)-tetrahydropalmatine; (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline; Tetrahydropalmatine; (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline; dl-Canadine; l-Tetrahydropalmatine; (-)-Tetrahydropalmatine; 2,3-methylenedioxy-9,10-dimethoxytetrahydroprotoberberine; Canadine dl-form; Canadin; tetrahydropulmatine
Molecular FormulaC21H25NO4
Molecular Weight355.427
Purity90%
Density1.2±0.1 g/cm3
Boiling Point482.9±45.0 °C at 760 mmHg
Melting Point155℃
AppearanceSolid;White to Orange to Green powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2934-97-6 |
| Catalog No. | 2A-9008730 |
| Chinese Name | 四氢帕马丁 |
| Synonyms | Berberine,tetrahydro; d,l-tetrahydropalmatine; (S)-tetrahydropalmatine; (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline; Tetrahydropalmatine; (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline; dl-Canadine; l-Tetrahydropalmatine; (-)-Tetrahydropalmatine; 2,3-methylenedioxy-9,10-dimethoxytetrahydroprotoberberine; Canadine dl-form; Canadin; tetrahydropulmatine |
| Molecular Formula | C21H25NO4 |
| Molecular Weight | 355.427 |
| Purity | 90 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 482.9±45.0 °C at 760 mmHg |
| Melting Point | 155℃ |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Storage Condition | Sealed in a cool, dry environment |
| Application | Tetrahydropalmatine, an active ingredient isolated from corydalis, inhibits epileptic seizures in rats by inhibiting dopamine release in the amygdala. |
| HTC | 2923900090 |
| SMILES | COc1cc2c(cc1OC)C1Cc3ccc(OC)c(OC)c3CN1CC2 |
| InChI | InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3 |
| InChI Key | AEQDJSLRWYMAQI-UHFFFAOYSA-N |
| Use of | Tetrahydropalmatine, an active component isolated from corydalis, acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. Properties Name rotundinum Synonym More Synonyms Tetrahydropalmatine Biological Activity Description Tetrahydropalmatine, an active component isolated from corydalis, acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. Related Catalog Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Natural Products >> Alkaloid Research Areas >> Neurological Disease Dopamine[1] References [1]. Chang CK, et al. DL-Tetrahydropalmatine may act through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. Neurosci Lett. 2001 Jul 20;307(3):163-6. Chemical & Physical Properties Molecular Formula C21H25NO4 Exact Mass 355.178345 PSA 40.16000 Index of Refraction 1.609 InChIKey AEQDJSLRWYMAQI-UHFFFAOYSA-N Safety Information HS Code 2923900090 Synthetic Route dihydropalmatin... 26067-60-7 Tetrahydropalma... Literature: Kiparissides, Zinovia; Fichtner, Robert H.; Poplawski, Janusz; Nalliah, Bala C.; MacLean, David B. Canadian Journal of Chemistry, 1980 , vol. 58, p. 2770 - 2779 dihydropalmatin... 75875-59-1 Tetrahydropalma... Literature: Kiparissides, Zinovia; Fichtner, Robert H.; Poplawski, Janusz; Nalliah, Bala C.; MacLean, David B. Canadian Journal of Chemistry, 1980 , vol. 58, p. 2770 - 2779 Tetrahydropalma... Literature: Narasimhan, N. S.; Ranade, A. C.; Bhide, B. H. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 6 p. 439 - 440 Precursor & DownStream Precursor 6 CAS#:81701-50-0 5,6,13,13a-tetr... CAS#:75875-59-1 dihydropalmatin... CAS#:104270-87-3 ethyl 6-formyl-... CAS#:120-20-7 3,4-Dimethoxyph... DownStream 2 CAS#:483-14-7 CAS#:4880-79-9 2,3,9,10-tetram... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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