
CAS Number1024-99-3
Synonyms5-Iodouridine; 5-Iod-uridin; 5-Iodoruidine; 2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine; 5-iodo-uridine; EINECS 213-833-1; 5-Jod-uridin; 5-Iodo-D-uridine; MFCD00006532
Molecular FormulaC9H11IN2O6
Molecular Weight370.10
Purity95%
Density2.3±0.1 g/cm3
Melting Point205-207 °C (dec.) (lit.)
Appearancepowder
EINECS213-833-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1024-99-3 |
| Catalog No. | 2A-9083191 |
| Chinese Name | 5-碘尿苷 |
| Synonyms | 5-Iodouridine; 5-Iod-uridin; 5-Iodoruidine; 2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine; 5-iodo-uridine; EINECS 213-833-1; 5-Jod-uridin; 5-Iodo-D-uridine; MFCD00006532 |
| Molecular Formula | C9H11IN2O6 |
| Molecular Weight | 370.10 |
| Purity | 95 |
| Density | 2.3±0.1 g/cm3 |
| Melting Point | 205-207 °C (dec.) (lit.) |
| Appearance | powder |
| Storage Condition | Store airtight at 2-8°C |
| Application | 5-iodouridine is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this process relies on in |
| EINECS | 213-833-1 |
| HTC | 2934999090 |
| PubChem ID | 24888326 |
| MDL Number | MFCD00006532 |
| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(I)C(=O)NC2=O |
| InChI | 1S/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1 |
| InChI Key | RKSLVDIXBGWPIS-UAKXSSHOSA-N |
| Beilstein/REAXYS | 33665 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/83191_1_1024_99_3.pdf |
| Bioactivity | 5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 2.3±0.1 g/cm3 Melting Point 205-207ºC (dec.)(lit.) Molecular Formula C9H11IN2O6 Molecular Weight 370.10 Exact Mass 369.966156 PSA 124.78000 LogP -0.43 Index of Refraction 1.748 Storage condition 2-8°C |
| Use of | 5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Articles10 Name 5-Iodouridine Synonym More Synonyms 5-Iodouridine Biological Activity Description 5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C9H11IN2O6 Exact Mass 369.966156 PSA 124.78000 LogP -0.43 Index of Refraction 1.748 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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