CAS Number6979-97-1
SynonymsThymidine,3',5'-diacetate; 2'-deoxy-3',5'-di-O-acetylthymidine; EINECS 230-244-5; DIACETYL THYMIDINE; 3',5'-di-O-acetyl-2'-desoxythymidine
Molecular FormulaC14H18N2O7
Molecular Weight326.30
Density1.37 g/cm3
Melting Point126 - 128ºC
AppearanceWhite crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6979-97-1 |
| Catalog No. | 2A-9083189 |
| Chinese Name | 3',5'-邸-O-乙酰胸苷 |
| Synonyms | Thymidine,3',5'-diacetate; 2'-deoxy-3',5'-di-O-acetylthymidine; EINECS 230-244-5; DIACETYL THYMIDINE; 3',5'-di-O-acetyl-2'-desoxythymidine |
| Molecular Formula | C14H18N2O7 |
| Molecular Weight | 326.30 |
| Density | 1.37 g/cm3 |
| Melting Point | 126 - 128ºC |
| Appearance | White crystalline powder |
| Storage Condition | Store at 0-6℃ |
| Application | 3',5'-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this process |
| SMILES | CC(=O)OCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1OC(C)=O |
| InChI Key | RGVBNBFNSBMXID-QJPTWQEYSA-N |
| Bioactivity | 3',5'-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 1.37 g/cm3 Melting Point 126 - 128ºC Molecular Formula C14H18N2O7 Molecular Weight 326.30 Exact Mass 326.11100 PSA 116.69000 Index of Refraction 1.549 InChIKey RGVBNBFNSBMXID-QJPTWQEYSA-N SMILES CC(=O)OCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1OC(C)=O |
| Use of | 3',5'-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 3',5'-diacetylthymidine Synonym More Synonyms Thymidine,3',5'-diacetate Biological Activity Description 3',5'-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C14H18N2O7 Exact Mass 326.11100 PSA 116.69000 Index of Refraction 1.549 InChIKey RGVBNBFNSBMXID-QJPTWQEYSA-N |
| Transport Info | Product name: ((2R,3S,5R)-3-acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-yl)tetrahydrofuran-2-yl)methylacetate |
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